NCT01041547|CompletedDMC
Vascular Function, Insulin Sensitivity, and Vitamin D
VIVID
Vitamin D, Vascular Function, and Insulin Sensitivity in Adults [The VIVID Study
Loading search results
VIVID
Vitamin D, Vascular Function, and Insulin Sensitivity in Adults [The VIVID Study
Sponsor study identifier
observational
63
1 country
1
Study Start
December 2009
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
December 2012
Actual (reported)Study Completion
December 2013
Actual (reported)The overall objectives of this study are to examine the relationships between circulating vitamin D, insulin sensitivity, and multiple indices of vascular function and to examine whether vitamin D deficiency in African Americans (AA) and White Hispanics (WH) is responsible for ethnic differences in insulin sensitivity and hypertension in AA, WH and European Americans (EA), as well as mechanisms underlying the association between insulin resistance and blood pressure. We hypothesize that 1) serum 25(OH)D is associated with insulin sensitivity and vascular functioning, independent of adiposity, 2) lower insulin sensitivity and vascular functioning in AA and WH relative to EA is due to lower circulating 25(OH)D in AA, and 3) the relationship between insulin resistance and vascular dysfunction is mediated by 25(OH)D. Acronyms: African American (AA), European American (EA), White Hispanics (WH), Serum 25-hydroxy vitamin D (25()H)D, Body mass index (BMI), Alabama (AL).
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2013
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
December 2009
Date type not reportedThis date has not been verified as actual or estimated.
December 28, 2009
Actual (reported)December 31, 2009
Actual (reported)December 2012
Actual (reported)December 2013
Actual (reported)Insulin sensitivity
Cross sectional study: at first study visit
Vascular function
Cross sectional study: at second study visit, within 2 weeks of first study visit
healthy adults with BMI below 32, between ages 19-60 yrs, both males and females
* Healthy adults with BMI below 32 * Both males and females * Ages 19-60 years * Race: African Americans, White Hispanics, European Americans
University of Alabama
Birmingham, Alabama, 35243, United States
Alvarez JA, Gower BA, Calhoun DA, Judd SE, Dong Y, Dudenbostel T, Scholl J, Ashraf AP. Serum 25-hydroxyvitamin D and Ethnic Differences in Arterial Stiffness and Endothelial Function. J Clin Med Res. 2012 Jun;4(3):197-205. doi: 10.4021/jocmr965w. Epub 2012 May 15.
Seum
Ambika Ashraf, MD
University of Alabama at Birmingham
63 participants (actual enrollment reported by the registry).
First Submitted
December 28, 2009
First Posted
December 31, 2009
Study Start
December 2009
Date type not reportedThis date has not been verified as actual or estimated.
Assessment of Influence of Vitamin D on Insulin Secretion and Sensitivity in Obese Teenage Girls
Contact the study team to confirm eligibility.
Primary Completion
December 2012
Actual (reported)Study Completion
December 2013
Actual (reported)Last Updated
January 14, 2014
Record last verified: 2014-01
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: