NCT01039922

Brief Summary

Gastroentero-pancreatic neuroendocrine tumours (GEP-NETs) are regarded as a fairly rare disease. They are derived from the neuroendocrine system of the gastrointestinal tract and the pancreas and share common clinical features. So far, there is still uncertainty about the cell biology and mechanistic regulation of these tumours. Therefore targeted treatment is limited and management challenging. Treatment options include surgery, medical and ablative therapy, and more recently peptide-receptor radionuclide therapy. In order to better understand the characteristics of GEP-NETs and to evaluate treatment strategies, the SwissNET registry aims at the collection of data from patients presenting with a GEP-NET in Switzerland. Data will be entered prospectively and anonymized in a specifically designed database after the patient has given informed consent. All hospitals and general practitioners are invited to report on patients with a GEP-NET diagnosis and to participate to the registry. Data will be evaluated within regular time frames, focussing on types of GEP-NETs, treatment modalities and patient outcomes (e.g. mortality, hospitalisation rate), thereby contributing to the better understanding of these tumours.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,245

participants targeted

Target at P75+ for all trials

Timeline
21mo left

Started Jan 2008

Longer than P75 for all trials

Geographic Reach
1 country

55 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress92%
Jan 2008Jan 2028

Study Start

First participant enrolled

January 1, 2008

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

December 24, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 25, 2009

Completed
18 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2028

Last Updated

January 23, 2020

Status Verified

January 1, 2020

Enrollment Period

20 years

First QC Date

December 24, 2009

Last Update Submit

January 20, 2020

Conditions

Keywords

Neuroendocrine TumorsRegistries

Outcome Measures

Primary Outcomes (1)

  • Tumor-related mortality

    Every 5 years

Secondary Outcomes (2)

  • Incidence of GEP-NET in Switzerland

    Every 5 years

  • Effect of specific treatment strategies

    Every 5 years

Study Arms (1)

1

Patients with a histologically confirmed diagnosis of a neuroendocrine tumor irrespective of primary tumor location

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients will be selected either through the report of a pathological institute or of any medical doctor within Switzerland treating patients with neuroendocrine tumours.

You may qualify if:

  • Neuroendocrine tumor irrespective of primary tumor location
  • Diagnosis in Switzerland
  • Given informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (55)

Kantonsspital Aarau

Aarau, Switzerland

RECRUITING

Spitalnetz Bern Aarberg

Aarberg, Switzerland

RECRUITING

Bezirksspital Affoltern

Affoltern am Albis, Switzerland

RECRUITING

Kantonsspital Uri, Altdorf

Altdorf, Switzerland

RECRUITING

St. Claraspital

Basel, Switzerland

RECRUITING

Universitätsspital Basel

Basel, Switzerland

RECRUITING

Istituto oncologico della Svizzera italiana

Bellinzona, Switzerland

RECRUITING

Div. of Endocrinology, Diabetes and Clinical Nutrition, Bern University Hospital

Bern, 3010, Switzerland

RECRUITING

Spital Tiefenau, Spitalnetz Bern

Bern, Switzerland

RECRUITING

Zieglerspital Bern

Bern, Switzerland

RECRUITING

Spitalzentrum Biel - Bienne

Biel, Switzerland

RECRUITING

Kantonsspital Bruderholz

Bruderholz, Switzerland

RECRUITING

Regionsspital Emmental

Burgdorf, Switzerland

RECRUITING

Kantonsspital Chur

Chur, Switzerland

RECRUITING

Private practise Dr. Mannhart

Churwalden, Switzerland

RECRUITING

Hôpital du Jura

Delémont, Switzerland

RECRUITING

Spital Dornach

Dornach, Switzerland

RECRUITING

Regionalspital Einsiedeln

Einsiedeln, Switzerland

RECRUITING

Hôpitaux Universitaires de Genève

Geneva, Switzerland

RECRUITING

Spital Grabs

Grabs, Switzerland

RECRUITING

See-Spital Horgen

Horgen, Switzerland

RECRUITING

Spital Zimmerberg

Horgen, Switzerland

RECRUITING

Fmi Spital Interlaken

Interlaken, Switzerland

RECRUITING

Spital Lachen

Lachen, Switzerland

RECRUITING

Spital Region Oberaargau

Langenthal, Switzerland

RECRUITING

Kantonsspital Laufen

Laufen, Switzerland

RECRUITING

Centre hospitalier universitaire vaudois, CHUV

Lausanne, Switzerland

RECRUITING

Kantonsspital Liestal

Liestal, Switzerland

RECRUITING

Hirslandenklinik St. Anna

Lucerne, Switzerland

RECRUITING

Kantonsspital Luzern

Lucerne, Switzerland

RECRUITING

Kantonsspital Sursee, Luzern

Lucerne, Switzerland

RECRUITING

Kreisspital Männedorf

Männedorf, Switzerland

RECRUITING

Kantonsspital Münsterlingen

Münsterlingen, Switzerland

RECRUITING

Kantonsspital Olten

Olten, Switzerland

RECRUITING

Gesundheitszentrum Fricktal

Rheinfelden, Switzerland

RECRUITING

Kantonsspital St. Gallen

Sankt Gallen, Switzerland

RECRUITING

Kantonsspital Obwalden

Sarnen, Switzerland

RECRUITING

Spital Limmattal

Schlieren, Switzerland

RECRUITING

Spital Schwyz

Schwyz, Switzerland

RECRUITING

Privatpraxis Dr. H.J. Poths

Seuzach Dorf, Switzerland

RECRUITING

Centre hospitalier du centre du Valais

Sion, Switzerland

RECRUITING

Bürgerspital Solothurn

Solothurn, Switzerland

RECRUITING

Kantonsspital Nidwalden

Stans, Switzerland

RECRUITING

Thun Spital STS AG

Thun, Switzerland

RECRUITING

Spital Uster

Uster, Switzerland

RECRUITING

Regionalspital Visp

Visp, Switzerland

RECRUITING

Kantonsspital Winterthur

Winterthur, Switzerland

RECRUITING

Kantonsspital Wolhusen

Wolhusen, Switzerland

RECRUITING

Spital Zollikerberg

Zollikerberg, Switzerland

RECRUITING

Zuger Kantonsspital AG

Zug, Switzerland

RECRUITING

Pathologie Medica Zürich

Zurich, Switzerland

RECRUITING

Stadtspital Triemli

Zurich, Switzerland

RECRUITING

Stadtspital Waid

Zurich, Switzerland

RECRUITING

Universitätsspital Zürich

Zurich, Switzerland

RECRUITING

STS AG Spital Zweisimmen

Zweisimmen, Switzerland

RECRUITING

MeSH Terms

Conditions

Neuroendocrine TumorsCarcinoid Tumor

Condition Hierarchy (Ancestors)

Neuroectodermal TumorsNeoplasms, Germ Cell and EmbryonalNeoplasms by Histologic TypeNeoplasmsNeoplasms, Nerve TissueAdenocarcinomaCarcinomaNeoplasms, Glandular and Epithelial

Study Officials

  • Aurel Perren, MD

    Institute of Pathology, University of Bern, Bern

    STUDY DIRECTOR

Central Study Contacts

Alexander Siebenhuener, MD

CONTACT

Emanuel Christ, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 24, 2009

First Posted

December 25, 2009

Study Start

January 1, 2008

Primary Completion (Estimated)

January 1, 2028

Study Completion (Estimated)

January 1, 2028

Last Updated

January 23, 2020

Record last verified: 2020-01

Locations