Key Insights

Highlights

Success Rate

81% trial completion

Published Results

57 trials with published results (16%)

Research Maturity

140 completed trials (39% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

8.9%

32 terminated out of 358 trials

Success Rate

81.4%

-5.1% vs benchmark

Late-Stage Pipeline

8%

28 trials in Phase 3/4

Results Transparency

41%

57 of 140 completed with results

Key Signals

57 with results81% success32 terminated

Data Visualizations

Phase Distribution

257Total
Not Applicable (32)
Early P 1 (11)
P 1 (66)
P 2 (120)
P 3 (20)
P 4 (8)

Trial Status

Completed140
Recruiting74
Unknown52
Active Not Recruiting33
Terminated32
Withdrawn12

Trial Success Rate

81.4%

Benchmark: 86.5%

Based on 140 completed trials

Clinical Trials (358)

Showing 20 of 20 trials
NCT04544098Early Phase 1Active Not RecruitingPrimary

Lutathera in People With Gastroenteropancreatic (GEP), Bronchial or Unknown Primary Neuroendocrine Tumors That Have Spread to the Liver

NCT02012699Recruiting

Integrated Cancer Repository for Cancer Research

NCT07314164RecruitingPrimary

Study of Cabozantinib in Participants With Neuroendocrine Tumors Who Have Already Received Prior Treatment

NCT06889493Phase 1Recruiting

SVV-001 With Nivolumab and Ipilimumab in Patients With Poorly Differentiated Neuroendocrine Carcinomas (NEC) or Well-Differentiated High-Grade Neuroendocrine Tumors (NET)

NCT01744249Phase 2CompletedPrimary

Sandostatin LAR and Axitinib vs Pbo in Pnts With Advanced Well-differentiated Non-pancreatic Neuroendocrine Carcinomas

NCT03412877Phase 2Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

NCT03206060Phase 2Recruiting

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

NCT00923026Enrolling By Invitation

Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies

NCT02174549Phase 1Recruiting

Dose-defining Study of Tirapazamine Combined With Embolization in Liver Cancer

NCT04074135Phase 2Recruiting

Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors

NCT07534371Active Not RecruitingPrimary

Analysis of Optimal Treatment Sequencing of Surufatinib and Somatostatin Analogs in Neuroendocrine Tumors: A Retrospective Cohort Study

NCT05153772Phase 2Active Not RecruitingPrimary

Targeted Alpha-emitter Therapy of PRRT Naïve and Previous PRRT Neuroendocrine Tumor Patients

NCT06638931Phase 2Recruiting

Agnostic Therapy in Rare Solid Tumors

NCT04375267Phase 1Completed

177Lu-DOTA-TATE and Olaparib in Somatostatin Receptor Positive Tumours

NCT05249114Phase 1Active Not RecruitingPrimary

Study of Cabozantinib With Lu-177 in Patients With Somatostatin Receptor 2 Positive Neuroendocrine Tumors

NCT07165132Phase 1Recruiting

Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

NCT04291885Phase 2Active Not Recruiting

Immunotherapy Adjuvant Trial in Patients With Stage I-III Merkel Cell Carcinoma

NCT04086485Phase 1Recruiting

Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)

NCT05477576Phase 3Recruiting

Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

NCT06041516Phase 1Recruiting

A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath Tumors

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