NCT01037933

Brief Summary

Primary aims: To compare changes in (a) symptoms related to cancer and chemotherapy, (b) a marker of immune function (salivary immunoglobulin A), and (c) a hormonal marker of emotional stress (salivary cortisol) between two groups of patients who view a humorous or non-humorous DVD. Secondary aim: To describe the perception of patients, caregivers, and nurses regarding the overall intervention experience.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for phase_2 cancer

Timeline
Completed

Started Feb 2007

Shorter than P25 for phase_2 cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2007

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2009

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

December 21, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 23, 2009

Completed
Last Updated

December 23, 2009

Status Verified

December 1, 2009

Enrollment Period

1.9 years

First QC Date

December 21, 2009

Last Update Submit

December 22, 2009

Conditions

Keywords

CancerHumorDistractionComedyChemotherapy

Outcome Measures

Primary Outcomes (1)

  • To compare changes in symptoms related to cancer and chemotherapy after a humor vs. non-humor intervention

    One day

Secondary Outcomes (1)

  • To compare changes in a marker of immune function (salivary immunoglobulin A), and a hormonal marker of emotional stress (salivary cortisol) between two groups of patients who view a humorous or non-humorous DVD.

    One day

Study Arms (2)

Humor intervention

ACTIVE COMPARATOR

A 45-minute humorous DVD ("Bananas Bunch") using a portable DVD player.

Other: Humor intervention

Non-humor intervention

ACTIVE COMPARATOR

A 45-minute non-humorous DVD "The A to Z of Steam Railways" using a portable DVD player.

Other: Non-humor intervention (distraction)

Interventions

A 45-minute humorous DVD ("Bananas Bunch") using a portable DVD player.

Humor intervention

A 45-minute non-humorous DVD ("The A to Z of Steam Railways") using a portable DVD player

Non-humor intervention

Eligibility Criteria

Age21 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of cancer
  • Receiving intravenous chemotherapy in the OPO clinic at QMC
  • Has a minimum appointment time in OPO of two hours
  • Age 21 or older
  • Speaks English

You may not qualify if:

  • Blind
  • Deaf
  • Diagnosis of head/neck cancer
  • Severe oral mucositis
  • Cognitively impaired

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Queen's Medical Center

Honolulu, Hawaii, 96813, United States

Location

Related Links

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Hob Osterlund, RN, MS

    The Queen's Medical Center

    PRINCIPAL INVESTIGATOR
  • Brad Willcox, MD

    The Queen's Medical Center

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 21, 2009

First Posted

December 23, 2009

Study Start

February 1, 2007

Primary Completion

January 1, 2009

Study Completion

January 1, 2009

Last Updated

December 23, 2009

Record last verified: 2009-12

Locations