NCT01034943

Brief Summary

Distal radius fractures are treated surgically if severely displaced. This study aims to investigate the outcome after surgery. The investigators will randomize patients to either external fixation with optional addition of k-wires or open reduction and fixation with a volar plate.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
70

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2009

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2009

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

December 16, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 18, 2009

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2013

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2014

Completed
Last Updated

March 13, 2014

Status Verified

March 1, 2014

Enrollment Period

3.5 years

First QC Date

December 16, 2009

Last Update Submit

March 12, 2014

Conditions

Keywords

radiusfracturewristexternalfixationvolarplateDASHPRWE

Outcome Measures

Primary Outcomes (1)

  • The primary outcome is measured by DASH (Disability of the Arm, Shoulder and Hand), which is a self administered questionnaire validated for disease and dysfunction of the upper limb.

    12 months

Secondary Outcomes (2)

  • A secondary outcome measure is the degree of malalignment on the x-ray of the injured wrist.

    12 months

  • A secondary outcome measure for this study is the EQ5D, a validated quality-of-life instrument.

    12 months

Study Arms (2)

External fixation

ACTIVE COMPARATOR

Operation with external fixation and optional addition of k-wire

Procedure: External fixation

Volar plate

ACTIVE COMPARATOR

Operation with Synthes volar two column plate (TCP)

Procedure: Volar plate

Interventions

Operation with external fixation and optional addition of k-wire

Also known as: External Fixation with Hoffman external fixator (Stryker)
External fixation
Volar platePROCEDURE

Operation with a Synthes volar two column plate (TCP)

Also known as: Synthes volar two column plate (TCP)
Volar plate

Eligibility Criteria

Age50 Years - 74 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Female 50-74 years or male 60-74 years
  • Dorsally displaced extraarticular distal radius fracture
  • Dorsal angulation \>20 degrees measured from the plane perpendicular to the radius axis
  • Low energy trauma
  • Injury \<72 hours when diagnosed
  • Patient independent of help for ADL

You may not qualify if:

  • Earlier dysfunction in any wrist
  • Other major injuries
  • Rheumatoid arthritis or other systemic joint disease
  • Dementia or severe psychiatric disease
  • Severe medical condition making general anesthesia a considerable risk

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Stockholm South Hospital Department of Orthopeadic Surgery

Stockholm, Stockholm County, 118 83, Sweden

Location

MeSH Terms

Conditions

Fractures, Bone

Interventions

External Fixators

Condition Hierarchy (Ancestors)

Wounds and Injuries

Intervention Hierarchy (Ancestors)

Orthopedic Fixation DevicesOrthopedic EquipmentSurgical EquipmentEquipment and SuppliesSurgical Fixation Devices

Study Officials

  • Sari Ponzer, Professor

    Karolinska Institutet

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, MD, Consultant orthopeadic surgeon

Study Record Dates

First Submitted

December 16, 2009

First Posted

December 18, 2009

Study Start

August 1, 2009

Primary Completion

February 1, 2013

Study Completion

February 1, 2014

Last Updated

March 13, 2014

Record last verified: 2014-03

Locations