Effect of Different Protein Diets on Glucose and Insulin Metabolism and Substrate Partitioning
1 other identifier
interventional
12
0 countries
N/A
Brief Summary
The purpose of this study is to determine whether different protein diets affects glucose and insulin metabolism and substrate partitioning.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Apr 2009
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2009
CompletedFirst Submitted
Initial submission to the registry
December 16, 2009
CompletedFirst Posted
Study publicly available on registry
December 17, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2010
CompletedAugust 23, 2018
August 1, 2018
9 months
December 16, 2009
August 21, 2018
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Glucose and insulin metabolism (24 h)
24 h
Secondary Outcomes (1)
Substrate partitioning and metabolic markers
24 h
Study Arms (4)
Control
EXPERIMENTALDiet consists of 15% dairy protein and low Glycemic Index (GI \< 40), 55 En% carbohydrates and 30 En% fat
High dairy protein
EXPERIMENTALDiet consists of 25% dairy protein and low GI (GI \< 40), 45 En% carbohydrates and 30 En% fat
vegetable protein
EXPERIMENTALDiet consists of 15 En% vegetable protein and low GI (GI \< 40), 55 En% carbohydrates and 30 En% fat
High GI
EXPERIMENTALDiet consists of 15 En% dairy protein and high GI(GI \> 60, 55 En% carbohydrates and 30 En% fat
Interventions
Diet consists of 15 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat
Diet consists of 25 En% dairy protein and low GI, 55 En% carbohydrates and 30 En% fat
Diet consists of 15 En% vegetable protein and low GI, 55 En% carbohydrates and 30 En% fat
Diet consists of 15 En% dairy protein and high GI, 55 En% carbohydrates and 30 En% fat
Eligibility Criteria
You may qualify if:
- BMI: 18.5-25 kg/m2 (lean)
- Gender: Male
- Age: \<35 years
- Caucasian
You may not qualify if:
- Elevated fasting blood glucose level
- Lactose intolerant
- Diabetes Mellitus
- Hypertension (systolic/diastolic blood pressure)
- Hypotension (systolic/diastolic blood pressure)
- Cardiovascular diseases
- Asthma and other obstructive pulmonary diseases
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Munsters MJ, Geraedts MC, Saris WH. Effects of different protein and glycemic index diets on metabolic profiles and substrate partitioning in lean healthy males. Appl Physiol Nutr Metab. 2013 Nov;38(11):1107-14. doi: 10.1139/apnm-2012-0409. Epub 2013 Apr 25.
PMID: 24053517DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Wim Saris, Prof. Dr.
Maastricht University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- PREVENTION
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 16, 2009
First Posted
December 17, 2009
Study Start
April 1, 2009
Primary Completion
January 1, 2010
Study Completion
March 1, 2010
Last Updated
August 23, 2018
Record last verified: 2018-08