Glasgow-Blatschford Score Validation in Digestive Hemorrhage
1 other identifier
interventional
208
1 country
1
Brief Summary
The purpose of this study is to validate the Glasgow-Blatchford score for the stratification of patients with upper gastro-intestinal hemorrhage. This score is easy to calculate. It is mainly based on the hemoglobin, blood pressure and blood urea. if the score is zero, the bleeding is very low risk and the gastrointestinal endoscopy may be delayed and performed as an outpatient.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Oct 2009
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2009
CompletedFirst Submitted
Initial submission to the registry
December 9, 2009
CompletedFirst Posted
Study publicly available on registry
December 10, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2014
CompletedJune 1, 2018
May 1, 2018
8 months
December 9, 2009
May 30, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Comparison of length of stay between patients with score equal to zero and above zero
june 2010
Secondary Outcomes (1)
Determination of the proportion of low risk upper gastrointestinal bleeding
june 2010
Study Arms (1)
Endoscopy
OTHERIf the Glasgow-Blatchford score is zero, the endoscopy is delayed as an outpatient
Interventions
Eligibility Criteria
You may qualify if:
- To be admitted in the university hospital for a gastrointestinal hemorrhage (vomiting of red or black blood or melena)
You may not qualify if:
- Age under 18
- Pregnancy
- Hemorrhage during hospitalisation
- red rectal bleeding
- No consent signed
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Geneva University Hospital
Geneva, 1211, Switzerland
Related Publications (2)
Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet. 2000 Oct 14;356(9238):1318-21. doi: 10.1016/S0140-6736(00)02816-6.
PMID: 11073021BACKGROUNDStanley AJ, Ashley D, Dalton HR, Mowat C, Gaya DR, Thompson E, Warshow U, Groome M, Cahill A, Benson G, Blatchford O, Murray W. Outpatient management of patients with low-risk upper-gastrointestinal haemorrhage: multicentre validation and prospective evaluation. Lancet. 2009 Jan 3;373(9657):42-7. doi: 10.1016/S0140-6736(08)61769-9. Epub 2008 Dec 16.
PMID: 19091393BACKGROUND
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marc Girardin, MD
University Hospital, Geneva
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- DIAGNOSTIC
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD
Study Record Dates
First Submitted
December 9, 2009
First Posted
December 10, 2009
Study Start
October 1, 2009
Primary Completion
June 1, 2010
Study Completion
December 1, 2014
Last Updated
June 1, 2018
Record last verified: 2018-05