NCT01022203

Brief Summary

The study is designed to evaluate the efficacy of a novel couple-based treatment for PTSD, called Structured Approach Therapy, to decrease PTSD and improve the marital and social functioning of Iraqi war Veterans and their partners. The effectiveness of couples therapy will be compared with the effectiveness of a couple-based educational intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
138

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2010

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 25, 2009

Completed
6 days until next milestone

First Posted

Study publicly available on registry

December 1, 2009

Completed
8 months until next milestone

Study Start

First participant enrolled

August 1, 2010

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
1.3 years until next milestone

Results Posted

Study results publicly available

March 9, 2015

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2016

Completed
Last Updated

November 16, 2016

Status Verified

October 1, 2016

Enrollment Period

3.3 years

First QC Date

November 25, 2009

Results QC Date

December 12, 2014

Last Update Submit

October 5, 2016

Conditions

Keywords

Couples TherapyPTSD

Outcome Measures

Primary Outcomes (1)

  • Psychological Functioning

    Clinician-Rated PTSD measured with the Clinician Administered PTSD Scale (Score range 0-133 with high scores indicating more severe PTSD); Self-Rated PTSD measured with the PTSD Checklist (Score range 17-85 with high scores indicating more severe PTSD).

    Pre-Treatment, Post-treatment (12 weeks), Follow-up (12 weeks after post-treatment).

Secondary Outcomes (2)

  • Relationship Functioning

    Pre-Treatment, Post-treatment (12 weeks), Follow-up (12 weeks after post-treatment).

  • Emotion Regulation

    Pre-Treatment, Post-treatment (12 weeks), Follow-up (12 weeks after post-treatment).

Study Arms (2)

Structured Approach Therapy

EXPERIMENTAL

Couple-Based Intervention called Structured Approach Therapy provides skills training to couple so they can reduce PTSD.

Behavioral: Structured Approach Therapy

PTSD Family Education

ACTIVE COMPARATOR

Couple-Based Education called PTSD Family Education teaches couple about PTSD symptoms, related problems, and treatment.

Other: PTSD Family Education

Interventions

The Structured Approach Therapy intervention includes education about the impact of PTSD on relationships; skills training to teach couples recognize and stop avoidance behavior; behavior activation training; emotion regulation training; and a couple-based intervention to teach Veterans with PTSD to identify and disclose trauma memories and related emotions to their partners. The couple is then trained to support disclosure while practicing empathic communication.

Structured Approach Therapy

The PTSD Family Education intervention provides education for Veterans with PTSD and their partners explaining the signs and symptoms of PTSD; psychological problems that are comorbid with PTSD; and treatments for PTSD. Skills training and psychotherapy are not included.

PTSD Family Education

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Exposure to at least one combat-related stressful event during combat deployment,
  • Current diagnostic criteria for PTSD for that event, and
  • Veteran is in a committed relationship and living with an opposite sex partner for at least six months.

You may not qualify if:

  • Current psychotic symptoms in either partner,
  • Current diagnosis of alcohol or drug dependence in either partner,
  • History of recent physical assault/abuse,
  • Currently receiving an evidence-based PTSD treatment (exposure-based or cognitive processing therapy)
  • Currently receiving couples therapy or family therapy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southeast Louisiana Veterans Health Care System, New Orleans, LA

New Orleans, Louisiana, 70112, United States

Location

Related Publications (2)

  • Sautter FJ, Glynn SM, Cretu JB, Senturk D, Vaught AS. Efficacy of structured approach therapy in reducing PTSD in returning veterans: A randomized clinical trial. Psychol Serv. 2015 Aug;12(3):199-212. doi: 10.1037/ser0000032.

  • Sautter FJ, Glynn SM, Becker-Cretu JJ, Senturk D, Armelie AP, Wielt DB. Structured Approach Therapy for Combat-Related PTSD in Returning U.S. Veterans: Complementary Mediation by Changes in Emotion Functioning. J Trauma Stress. 2016 Aug;29(4):384-7. doi: 10.1002/jts.22120. Epub 2016 Jul 29.

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Limitations and Caveats

The study's small sample size makes results preliminary and precludes formal hypothesis testing of mediating variables. Our report of decreased PTSD may reflect regression toward the mean.

Results Point of Contact

Title
Frederic Sautter, Ph.D.
Organization
Southeast Louisiana Veterans Health Care System (SLVHCS)

Study Officials

  • Frederic J Sautter, PhD

    Southeast Louisiana Veterans Health Care System, New Orleans, LA

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 25, 2009

First Posted

December 1, 2009

Study Start

August 1, 2010

Primary Completion

December 1, 2013

Study Completion

October 1, 2016

Last Updated

November 16, 2016

Results First Posted

March 9, 2015

Record last verified: 2016-10

Data Sharing

IPD Sharing
Will not share

Locations