The Effect of Osteopathic Manual Therapy on Vascular Supply

NCT01020591 | Completed Results

• 1 other identifier: CDHA-RS/2010-227
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine if the use of osteopathic manual therapy can influence the vascular supply to the knee, knee range of motion, balance and knee pain, in a group of subjects with knee osteoarthritis. It is also the objective of this study to determine if there is a difference between the osteopathic evaluation and the combination of an osteopathic evaluation and treatment.

Conditions

Knee Osteoarthritis

Keywords

knee osteoarthritis; manual therapy; osteopathy

Outcome Measures

Primary Outcomes (1)

• Resistive Index (RI)

  Ultrasonographic examination provides a non-invasive method to assess blood flow dynamics. The resistive index (RI), calculated from arterial blood flow velocities, reflects vascular resistance. The RI was calculated by dividing the peak systolic velocity (PSV) minus the end-diastolic velocity by the peak systolic velocity, and is cited frequently in the literature for measuring hemodynamics of peripheral vessels.

  Participants attended one visit; The outcome measure (RI) was before and after an osteopathic session on the same day; The data collection of the 30 subjects took place between Jan to March 2010; each subject had outcomes measured on one day

Secondary Outcomes (1)

• The Knee Flexion Active Range of Motion, Balance and Pain (VAS)

  Jan 2010 to March 2010

Study Arms (2)

Osteopathic evaluation

ACTIVE COMPARATOR

osteopathic evaluation of motion and tissue mobility

Other: Osteopathic evaluation

Osteopathic evaluation with treatment

EXPERIMENTAL

osteopathic evaluation of motion and tissue mobility followed by osteopathic manual therapy release of the tight or restricted tissues

Other: Osteopathic evaluation with treatment

Interventions

Osteopathic evaluation OTHER

evaluation of movement and tissue mobility

Osteopathic evaluation

Osteopathic evaluation with treatment OTHER

osteopathic evaluation followed by osteopathic manual therapy release of tissues identified as tight or restricted

Osteopathic evaluation with treatment

Eligibility Criteria

• Age: 50 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Radiographic-confirmed knee osteoarthritis

You may not qualify if:

• Subjects who are unable to ambulate independently (without an aid) and safely the distance of a city block
• Subjects who have an uncontrolled medical condition (e.g. heart (angina) or respiratory condition (asthma))
• Subjects who have a neurological condition (e.g. Parkinson's, Multiple Sclerosis)
• Subjects who have both knees affected by osteoarthritis and have had previous surgery to both knees
• Subjects who have knee OA in only one knee and that knee has had previous knee surgery
• Subjects who have previous vascular surgery to either leg

Sponsors & Collaborators

• Nova Scotia Health Authority: lead

Study Sites (1)

Capital District Health Authority

Halifax, Nova Scotia, B3H 1V7, Canada

Location

MeSH Terms

Conditions

Osteoarthritis, Knee

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Results Point of Contact

• Title: Wendy Jardine
• Organization: CDHA

wendymjardine@gmail.com

902 429 6218

Study Officials

• Wendy M Jardine, MScPT

  Nova Scotia Health Authority

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist osteopath

Study Record Dates

• First Submitted: November 24, 2009
• First Posted: November 25, 2009
• Study Start: December 1, 2009
• Primary Completion: March 1, 2010
• Study Completion: March 1, 2010
• Last Updated: May 4, 2017
• Results First Posted: May 4, 2017

Record last verified: 2017-03

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)