The Darlington Retrospective Outpatient Study

NCT01013883 | Completed Results

• 1 other identifier: RajPh.D2066
• Study Type: observational
• Target: 509
• Locations: 1 country
• Sites: 1

Brief Summary

Having heart failure means the heart is unable to pump blood around the body effectively. This reduces life expectancy and hinders normal daily activities. Heart failure affects about one million people in the UK; it is a major cause of death but it is often undetected and under-treated. If diagnosed and treated properly, the symptoms of heart failure can be well controlled and the length and quality of life can be improved. Two drugs (called ACE-inhibitors and beta-blockers) help patients to live longer and suffer fewer consequences of heart failure. These drugs should be offered to all patients although this does not happen consistently for a variety of reasons. Doctors specialising in heart failure may help patients make better informed decisions about treatments and other aspects of care. The purpose of this research is to explore the diagnosis, management and outcome of patients with heart failure who are referred to the one stop diagnostic heart failure clinic between Jan 2002 and Dec 2007. This study will provide vital information about diagnosis, initiation and titration of evidence based medication in the hospital, their follow in the primary care and subsequent patient outcome in terms of mortality.

Conditions

Heart Failure

Keywords

systolic dysfunction; diastolic dysfunction; mortality; treatment; heart rate

Outcome Measures

Primary Outcomes (1)

• All Cause Mortality

  Patients would be followed up for average of 7 years

Secondary Outcomes (2)

• Cardiovascular Mortality

  Patients would be followed up for average of 7years

• Admission to Hospital for Any Cause

  During the follow up period of 7 years

Study Arms (2)

systolic dysfunction

patients having left ventricular systolic dysfunction on echocardiography

distolic heart failure

patients with clinical heart failure and preserved LV systolic dysfunction

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Secondary care one stop diagnostic heart failure clinic

You may qualify if:

• years and over attending heart failure clinic between 01/01/2002- 31/12/07

You may not qualify if:

• less than 18 years.
• Pregnant females

Sponsors & Collaborators

• County Durham and Darlington NHS Foundation Trust: lead
• University of Durham: collaborator

Study Sites (1)

Darlington Memorial Hospital

Darlington, Durham, DL3 6HX, United Kingdom

Location

MeSH Terms

Conditions

Heart Failure

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Results Point of Contact

• Title: Dr Rajender singh
• Organization: Darlington Memorial Hospital

drrsdogra@yahoo.com

01325380100

Study Officials

• Rajender Singh, MD

  county durham and darlington NHS trust

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research registrar

Study Record Dates

• First Submitted: November 13, 2009
• First Posted: November 16, 2009
• Study Start: January 1, 2010
• Primary Completion: August 1, 2011
• Study Completion: August 1, 2011
• Last Updated: March 14, 2014
• Results First Posted: March 14, 2014

Record last verified: 2014-01

Locations

GB (1)