NCT00986830

Brief Summary

A prospective, nonrandomized trial to evaluate postoperative healthcare resource utilization after maxillary balloon antrostomy using FinESS Sinus Treatment in the physician's office.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
74

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2009

Typical duration for not_applicable

Geographic Reach
1 country

13 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2009

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

September 29, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 30, 2009

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2012

Completed
8.2 years until next milestone

Results Posted

Study results publicly available

October 27, 2020

Completed
Last Updated

October 27, 2020

Status Verified

October 1, 2020

Enrollment Period

3 years

First QC Date

September 29, 2009

Results QC Date

September 15, 2020

Last Update Submit

October 6, 2020

Conditions

Keywords

RhinosinusitisBalloon cathetersOffice treatmentOtorhinolaryngologic diseasesRespiratory tract infectionsRespiratory tract diseasesFinESS Sinus TreatmentEndoscopic sinus surgery

Outcome Measures

Primary Outcomes (1)

  • Sino-Nasal Outcomes Test

    The 20-item Sino-Nasal Outcomes Test (SNOT-20) is a validated, disease-specific patient-reported instrument designed to indicate the severity of rhinosinusitis symptoms. The SNOT-20 evaluates 20 symptoms on a scale from 0 ("no problem") to 5 ("problem as bad as it can be"). The overall SNOT-20 score is the average of the 20 symptoms scores providing a range from 0 to 5 with higher scores indicating worse symptoms. The minimal clinically important difference (MCID) has been determined to be a reduction of 0.8 or more in the overall SNOT-20 score.

    Baseline and 12 months post procedure

Secondary Outcomes (8)

  • Rhinosinusitis Symptom Inventory (RSI) Nasal Symptoms Domain

    Baseline and 12 months post procedure

  • Rhinosinusitis Symptom Inventory (RSI) Facial Symptoms Domain

    Baseline and 12 months post procedure

  • Rhinosinusitis Symptom Inventory (RSI) Oropharyngeal Symptoms Domain

    Baseline and 12 months post procedure

  • Rhinosinusitis Symptom Inventory (RSI) Systemic Symptoms Domain

    Baseline and 12 months post procedure

  • Number of Participants Using Nasal Steroids

    Baseline and 12 months post procedure

  • +3 more secondary outcomes

Study Arms (1)

Balloon Dilation

EXPERIMENTAL

Balloon dilation of the maxillary sinuses using the FinESS Sinus Treatment device.

Device: FinESS Sinus Treatment

Interventions

Balloon Dilation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older
  • Male or female subjects
  • Diagnosis of rhinosinusitis (CT radiographic evidence and medical evaluation)
  • Willing to comply with protocol requirements
  • Able to provide consent

You may not qualify if:

  • Hemophilia
  • Cystic fibrosis
  • Ciliary dysfunction
  • Severe septal deviation causing obstruction of the ostiomeatal unit
  • Pregnant females

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (13)

Central California ENT

Fresno, California, 93720, United States

Location

South Denver ENT and Allergy

Denver, Colorado, 80120, United States

Location

ENT and Allergy Associates

Trumbull, Connecticut, 06611, United States

Location

NorthShore University

Evanston, Illinois, 60201, United States

Location

Advanced ENT and Allergy

Louisville, Kentucky, 40207, United States

Location

St. Cloud Ear, Nose and Throat

Saint Cloud, Minnesota, 56303, United States

Location

Coastal Ear, Nose and Throat Associates

New Bern, North Carolina, 28562, United States

Location

Midwest Ear, Nose and Throat

Sioux Falls, South Dakota, 57108, United States

Location

Holston Medical Center

Kingsport, Tennessee, 37660, United States

Location

Austin Ear, Nose and Throat

Austin, Texas, 78705, United States

Location

Texas Sinus Center

Boerne, Texas, 78006, United States

Location

The Snoring Center

Dallas, Texas, 75205, United States

Location

Advanced Otolaryngology PC

Richmond, Virginia, 23235, United States

Location

Related Publications (1)

  • Levine SB, Truitt T, Schwartz M, Atkins J. In-office stand-alone balloon dilation of maxillary sinus ostia and ethmoid infundibula in adults with chronic or recurrent acute rhinosinusitis: a prospective, multi-institutional study with-1-year follow-up. Ann Otol Rhinol Laryngol. 2013 Nov;122(11):665-71. doi: 10.1177/000348941312201101.

MeSH Terms

Conditions

RhinosinusitisOtorhinolaryngologic DiseasesRespiratory Tract InfectionsRespiratory Tract Diseases

Condition Hierarchy (Ancestors)

RhinitisInfectionsSinusitisParanasal Sinus DiseasesNose Diseases

Results Point of Contact

Title
Principal Clinical Research & Publications Manager
Organization
Stryker ENT

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 29, 2009

First Posted

September 30, 2009

Study Start

September 1, 2009

Primary Completion

September 1, 2012

Study Completion

September 1, 2012

Last Updated

October 27, 2020

Results First Posted

October 27, 2020

Record last verified: 2020-10

Data Sharing

IPD Sharing
Will not share

Locations