NCT00986271

Brief Summary

To investigate whether extravascular lung water index (EVLI) is an independent predictor for multiorgan dysfunction syndrome (MODS) in patients with severe sepsis and to determine if increased EVLI may serve as an predictor for MODS and mortality in those patients.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
67

participants targeted

Target at P50-P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 27, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 29, 2009

Completed
Last Updated

September 29, 2009

Status Verified

April 1, 2008

First QC Date

September 27, 2009

Last Update Submit

September 28, 2009

Conditions

Keywords

severe sepsis, intensive care units

Outcome Measures

Primary Outcomes (1)

  • Developement of MODS (multiorgan dysfunction syndrome) and mortality

Study Arms (1)

With and without MODS developement

OTHER

EVLI was determinated by PiCCO plus system.

Procedure: EVLI was determinated by PiCCO plus system.

Interventions

With and without MODS developement

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • All enrolled patients were recruited consecutively on the day of MICU admission and within 24 hours of the diagnosis of severe sepsis.

You may not qualify if:

  • Pregnancy,
  • Age less than 18 years old, and
  • Uncontrolled malignancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Sepsis

Interventions

Drug Delivery Systems

Condition Hierarchy (Ancestors)

InfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Drug TherapyTherapeutics

Study Design

Study Type
interventional
Phase
not applicable
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 27, 2009

First Posted

September 29, 2009

Last Updated

September 29, 2009

Record last verified: 2008-04