NCT00981019

Brief Summary

The probably most commonly used measure for expressing the pay-offs of early detection and treatment are survival rates. Yet, over time and groups this metric comes with several biases and thus, is not reliable for judging such benefits. Epidemiologists recommend using reduction of disease-specific mortality rates instead, which is unbiased. The purpose of the study is to investigate how primary care physicians understand and use different survival measures for determining the benefit of cancer screening tests.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
778

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 18, 2009

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 22, 2009

Completed
2 months until next milestone

Study Start

First participant enrolled

December 1, 2009

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
1.7 years until next milestone

Results Posted

Study results publicly available

August 15, 2011

Completed
Last Updated

August 15, 2011

Status Verified

July 1, 2011

Enrollment Period

Same day

First QC Date

September 18, 2009

Results QC Date

May 20, 2011

Last Update Submit

July 20, 2011

Conditions

Keywords

survival ratesrisk communicationscreening counsellingscreening recommendationunderstanding of medical risk

Outcome Measures

Primary Outcomes (1)

  • Number of Physicians (=Participants) Recommending the Screening

    The aim of the study was to learn how different medical cancer screening statistics would influence doctors' recommendation behavior and their effectiveness judgments of screening tests. For that reason the online survey study presented physicians with four different medical statistics (e.g., 5-year survival) within four successive scenarios and asked after each scenario whether they would recommend the screening to a (hypothetical) patient given the data. Options to answer are: Definitely yes, Probably yes, Probably no, Definitely no, Can't decide.

    25 minutes (mean duration of the survey)

Secondary Outcomes (1)

  • Number of Physicians (= Participants) Assuming a Benefit of Screening

    25 minutes (mean duration of the survey)

Study Arms (1)

mortality*incidence*5-year survival*early stage

Physicians will be faced in scenarios about screening with information on mortality and 5-year survival, followed by information on mortality\*incidence and 5-year survival\*early stage in a random order.

Eligibility Criteria

Age30 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

301 primary care physicians (internal, general, and family medicine physicians)

You may qualify if:

  • primary care physicians (internal, general, and family medicine physicians)

You may not qualify if:

  • all other types of physicians

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Max Planck Institute for Human Development

Berlin, 14195, Germany

Location

Related Publications (1)

  • Wegwarth O, Schwartz LM, Woloshin S, Gaissmaier W, Gigerenzer G. Do physicians understand cancer screening statistics? A national survey of primary care physicians in the United States. Ann Intern Med. 2012 Mar 6;156(5):340-9. doi: 10.7326/0003-4819-156-5-201203060-00005.

Related Links

Limitations and Caveats

Mistaken exclusion of "exclusively outpatient" physicians due to a programming mistake of the online survey screener

Results Point of Contact

Title
Dr. Odette Wegwarth
Organization
Max Planck Institute for Human Development, Harding Center for Risk Literacy

Study Officials

  • Odette Wegwarth, Dr.

    Max Planck Institute for Human Development

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 18, 2009

First Posted

September 22, 2009

Study Start

December 1, 2009

Primary Completion

December 1, 2009

Study Completion

December 1, 2009

Last Updated

August 15, 2011

Results First Posted

August 15, 2011

Record last verified: 2011-07

Locations