Initiative in LYon for Lung cAncer Screening Development - Prevalence Study

NCT04240418 | Completed

• 1 other identifier: ILYAD1_2019
• Study Type: observational
• Target: 4,595
• Locations: 1 country
• Sites: 1

Brief Summary

Screening at-risk subjects with low-dose computed tomography (CT) efficiently reduces lung cancer specific mortality. However screening efficiency relies on the at-risk population's criteria definition and its participation rate to the screening. In France, there are concerns regarding the participation rates to national cancer screening that are quite low (around 50% and 32% of the eligible population for breast cancer and colorectal cancer respectively). Before organizing national lung cancer screening it is then crucial to determine the factors impacting the at-risk subjects willingness to participate in lung cancer screening. The Lyon University Hospital is the second biggest hospital in France with more than 23,000 employees distributed among more than 160 professions representing every level of education or working conditions. Its population is heterogeneous and wide enough to perform a prevalence study assessing the willingness to participate among the at-risk population. ILYAD is a prospective study performed by anonymous questionnaires that will be submitted to the 23,000 employees of the Lyon University Hospital. The study main objective is to evaluate the at-risk population presence in the Lyon University Hospital population, as defined by NELSON criteria and selection criteria for lung cancer screening (PLCOm2012 scoring), and its willingness to participate to a lung-cancer screening with low-dose CT. This might help further efficient national lung cancer screening campaign organization.

Conditions

Lung Cancer; Screening

Outcome Measures

Primary Outcomes (1)

• Number of employees belonging to the at-risk population for lung cancer and consequently eligible to lung cancer screening.

  High-risk ever-smokers are defined as ever-smokers aged 55-74 years old, having smoked \>15 cigarettes per day for \>25 years or \>10 cigarettes for \>30 years and with ≤15 years since cessation for quitters.

  Day 0 (at inclusion)

Study Arms (1)

Lyon University Hospital employees

Other: Survey

Interventions

Survey OTHER

The objective is to evaluate the eligibility of the responders, as defined by NELSON criteria and PLCOm2012 scoring, and their willingness to participate to a lung-cancer screening with low-dose computed tomography.

Lyon University Hospital employees

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The Civil Hospices of Lyon is the second largest university hospital in France, with 23000 staff.

You may qualify if:

• Aged ≥ 18 years old
• Employee from the Lyon University Hospital (receiving salary from the Lyon University Hospital)
• Person who has willingness to respond the survey

You may not qualify if:

• Employees not hired by the Lyon University Hospital
• Employees who have not willingness to participate in the survey

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

Hospices Civils de Lyon

Lyon, 69000, France

Location

MeSH Terms

Conditions

Lung Neoplasms

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 22, 2020
• First Posted: January 27, 2020
• Study Start: October 31, 2020
• Primary Completion: January 14, 2021
• Study Completion: January 14, 2021
• Last Updated: July 13, 2021

Record last verified: 2021-07

Locations

FR (1)