Passport to Brain Wellness in Sedentary Adults

NCT00979446 | Completed DMC

• 2 other identifiers: 03-024S23R01AG023410-05S2
• Study Type: interventional
• Target: 63
• Locations: 1 country
• Sites: 1

Brief Summary

Numerous modifiable lifestyle factors have been identified that may affect the risk of older adults developing mild cognitive impairment (MCI) and Alzheimer's disease (AD). Evidence suggests that interventions to reduce risk factors and enhance protective factors would be beneficial in slowing cognitive decline and decreasing the risk of incident MCI and AD. The overall objective of this pilot study, funded as a supplement to Keep Active Minnesota (KAM) (03-024; R01-AG023410) is to develop and test the feasibility of conducting a multi-domain intervention to maintain cognitive health in adults ages 60-80 with the goal of reducing the incidence of and slowing progression to MCI and other more severe forms of cognitive decline.

Conditions

Mild Cognitive Impairment; Alzheimer's Disease

Keywords

Interactive phone-based intervention with written materials; Older adults; Physical activity; Cognitive stimulation; Social engagement

Outcome Measures

Primary Outcomes (1)

• We will use this pilot to determine the feasibility of carrying out a full-scale randomized trial to test the efficacy of our intervention.

  Six months after the baseline visit

Study Arms (2)

Guided

EXPERIMENTAL

Behavioral: Guided

Self-directed

ACTIVE COMPARATOR

Behavioral: Self-directed

Interventions

Guided BEHAVIORAL

Engaged in a 4 month pilot of a multi-domain lifestyle intervention with a phone coach

Guided

Self-directed BEHAVIORAL

Received study materials but no phone coaching

Self-directed

Eligibility Criteria

• Age: 60 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adults between the ages of 60 and 80
• Have had HealthPartners insurance for 11 out of the 12 months prior to recruitment
• Engage in less than 90 minutes per week of moderate intensity physical activity
• Works or volunteers 20 hours total per week or less
• Telephone Interview for Cognitive Status (TICS) score of 31 and above

You may not qualify if:

• Modified Charlson scores \>=3 (calculated using prior year diagnoses)
• Nonskin cancer
• Congestive heart failure
• Coronary heart disease
• Psychotic Illness
• Substance abuse
• Terminal illness

Sponsors & Collaborators

• HealthPartners Institute: lead

Study Sites (1)

HealthPartners Research Foundation

Bloomington, Minnesota, 55425, United States

Location

MeSH Terms

Conditions

Cognitive Dysfunction; Alzheimer Disease; Motor Activity

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Dementia; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Tauopathies; Neurodegenerative Diseases; Behavior

Study Officials

• Brian C Martinson, PhD

  HealthPartners Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 16, 2009
• First Posted: September 18, 2009
• Study Start: June 1, 2008
• Primary Completion: May 1, 2009
• Study Completion: August 1, 2009
• Last Updated: September 18, 2009

Record last verified: 2009-09

Locations

US (1)