NCT00972621

Brief Summary

The purpose of this study is to evaluate the safety and effectiveness of a new opthalmic viscoelastic material for the use in cataract surgery. The new viscoelastic will be compared to a currently marketed viscoelastic material.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 3, 2009

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 7, 2009

Completed
23 days until next milestone

Study Start

First participant enrolled

September 30, 2009

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 30, 2010

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

February 22, 2012

Completed
Last Updated

February 11, 2025

Status Verified

February 1, 2025

Enrollment Period

1.2 years

First QC Date

September 3, 2009

Results QC Date

January 18, 2012

Last Update Submit

February 10, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Percent of Intraocular Pressure Spikes 30 mm Hg or Greater Postoperatively

    Cumulative rate of Intraoperative Pressure (IOP) spikes 30 mm Hg (millimeters of mercury) or greater measured postoperatively through three months.

    3 months postoperative

Secondary Outcomes (1)

  • Postoperative Mean Endothelial Cell Count

    3 months postoperative

Study Arms (2)

Vitrax II

EXPERIMENTAL

Investigational dispersive viscoelastic

Device: Vitrax II

Viscoat

ACTIVE COMPARATOR

Marketed control dispersive viscoelastic

Device: Viscoat

Interventions

Vitrax IIDEVICE

Viscoelastic administered via one or two vials as determined by cataract surgeon for maintenance of anterior chamber.

Vitrax II
ViscoatDEVICE

Currently marketed viscoelastic administered via one or two vials as determined by cataract surgeon for maintenance of anterior chamber..

Viscoat

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Otherwise healthy eye with no pathology other than the presence of cataract
  • Visual potential of 20/40 or better

You may not qualify if:

  • Taking any medications that affect vision, intraocular pressure or ease of cataract surgery (e.g. flomax, glaucoma medications, etc.)
  • Known intraocular pressure increases from steroid treatment
  • Low endothelial cell count

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AMO Clinical Research Call Center for Trial Locations

Santa Ana, California, 92799, United States

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Results Point of Contact

Title
Kendra Hileman, Ph.D., Head, Clinical Research & Development
Organization
Abbott Medical Optics, Inc.

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 3, 2009

First Posted

September 7, 2009

Study Start

September 30, 2009

Primary Completion

November 30, 2010

Study Completion

November 30, 2010

Last Updated

February 11, 2025

Results First Posted

February 22, 2012

Record last verified: 2025-02

Locations