NCT00967200

Brief Summary

RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at tissue samples from patients with glioma or other brain tumors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
180

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Nov 2003

Longer than P75 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2003

Completed
5.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2009

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

August 26, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 27, 2009

Completed
6.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2015

Completed
Last Updated

November 24, 2015

Status Verified

November 1, 2015

Enrollment Period

5.7 years

First QC Date

August 26, 2009

Last Update Submit

November 23, 2015

Conditions

Central Nervous System Lymphoma

Keywords

adult anaplastic astrocytomaadult diffuse astrocytomaadult glioblastomaadult giant cell glioblastomaadult gliosarcomaadult pilocytic astrocytomaadult pineal gland astrocytomaadult subependymal giant cell astrocytomaadult brain stem gliomaadult choroid plexus tumoradult craniopharyngiomaadult ependymoblastomaadult medulloblastomaadult supratentorial primitive neuroectodermal tumor (PNET)adult anaplastic ependymomaadult ependymomaadult myxopapillary ependymomaadult subependymomameningeal melanocytomaadult meningeal hemangiopericytomaadult grade I meningiomaadult grade II meningiomaadult anaplastic meningiomaadult papillary meningiomaadult anaplastic oligodendrogliomaadult oligodendrogliomaadult pineoblastomaadult pineocytomaadult mixed gliomarecurrent adult brain tumor

Outcome Measures

Primary Outcomes (1)

  • Pathophysiology of gliomas

    Pathophysiology of gliomas that may predict prognosis and progression or that could identify new therapeutic

    1 day

Secondary Outcomes (1)

  • Identification of molecular

    1 day

Interventions

laboratory biomarker analysisOTHER

laboratory biomarker analysis

pharmacogenomic studiesOTHER

pharmacogenomic studies

Eligibility Criteria

Age18 Years - 120 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Pathophysiology of gliomas and identification of molecular markers that may predict prognosis and progression or that could identify new therapeutic

Inclusion Histologically confirmed glioma of any grade or rare primary brain tumor No urgent situation No known or suspected active infection Must not be deprived of liberty or protected by law Not pregnant or nursing Exclusion : No concurrent participation in other trials that require a period of exclusion

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (2)

CHU Montpellier

Montpellier, 34295, France

Location

Clinique Gui de Chauliac

Montpellier, 34295, France

Location

MeSH Terms

Conditions

AstrocytomaGlioblastomaGliosarcomaChoroid Plexus NeoplasmsCraniopharyngiomaNeuroectodermal Tumors, PrimitiveMedulloblastomaEpendymomaGlioma, SubependymalMeningiomaOligodendrogliomaPinealomaGliomaBrain Neoplasms

Interventions

Pharmacogenomic Testing

Condition Hierarchy (Ancestors)

Neoplasms, NeuroepithelialNeuroectodermal TumorsNeoplasms, Germ Cell and EmbryonalNeoplasms by Histologic TypeNeoplasmsNeoplasms, Glandular and EpithelialNeoplasms, Nerve TissueCerebral Ventricle NeoplasmsCentral Nervous System NeoplasmsNervous System NeoplasmsNeoplasms by SiteBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeoplasms, Vascular TissueMeningeal Neoplasms

Intervention Hierarchy (Ancestors)

Genetic TestingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisInvestigative TechniquesGenetic TechniquesGenetic ServicesHealth ServicesHealth Care Facilities Workforce and ServicesDiagnostic ServicesPreventive Health Services

Study Officials

  • Luc Bauchet, MD

    University Hospital, Montpellier

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 26, 2009

First Posted

August 27, 2009

Study Start

November 1, 2003

Primary Completion

July 1, 2009

Study Completion

November 1, 2015

Last Updated

November 24, 2015

Record last verified: 2015-11

Locations

FR(2)