Study of Blood and Tumor Samples From Men With an Inherited Risk of Prostate Cancer
UK Genetic Prostate Cancer Study
3 other identifiers
observational
21,000
1 country
135
Brief Summary
RATIONALE: Studying samples of blood and tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify genes related to cancer. PURPOSE: This clinical trial is studying blood and tumor samples from men with an inherited risk of prostate cancer.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
135 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 1993
CompletedFirst Submitted
Initial submission to the registry
August 13, 2009
CompletedFirst Posted
Study publicly available on registry
August 14, 2009
CompletedAugust 26, 2013
August 1, 2009
August 13, 2009
August 23, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Prostate cancer (PC) predisposition (PCP) genes
Secondary Outcomes (7)
Association of PCP genes with disease and treatment parameters
Association of PCP with environmental factors
Family history of PC
Relative risk of developing PC
Increased risk relatives of PC patients are to develop cancers other than PC
- +2 more secondary outcomes
Interventions
Eligibility Criteria
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Sponsors & Collaborators
Study Sites (135)
William Harvey Hospital
Ashford-Kent, England, TN24 0LZ, United Kingdom
Tameside General Hospital
Ashton-under-Lyne, England, OL6 9RW, United Kingdom
Stoke Mandeville Hospital
Aylesbury-Buckinghamshire, England, HP21 8AL, United Kingdom
North Devon District Hospital
Barnstaple, England, EX31 4JB, United Kingdom
Furness General Hospital
Barrow in Furness, England, LA14 4LF, United Kingdom
Basildon University Hospital
Basildon, England, SS16 5NL, United Kingdom
Basingstoke and North Hampshire NHS Foundation Trust
Basingstoke, England, RG24 9NA, United Kingdom
Royal United Hospital
Bath, England, BA1 3NG, United Kingdom
Primrose Centre at Bedford Hospitals NHS Trust
Bedford, England, MK42 9DJ, United Kingdom
Queen Elizabeth Hospital at University Hospital of Birmingham NHS Trust
Birmingham, England, B15 2TH, United Kingdom
City Hospital - Birmingham
Birmingham, England, B18 7QH, United Kingdom
Good Hope Hospital
Birmingham, England, B75 7RR, United Kingdom
Birmingham Heartlands Hospital
Birmingham, England, B9 5SS, United Kingdom
Royal Blackburn Hospital
Blackburn, England, BB2 3 HH, United Kingdom
Blackpool Victoria Hospital
Blackpool, England, FY3 8NR, United Kingdom
Pilgrim Hospital
Boston, England, PE21 9QT, United Kingdom
Royal Bournemouth Hospital
Bournemouth, England, BH7 7DW, United Kingdom
Sussex Cancer Centre at Royal Sussex County Hospital
Brighton, England, BN2 5BE, United Kingdom
Southmead Hospital
Bristol, England, BS10 5NB, United Kingdom
Frenchay Hospital
Bristol, England, BS16 1LE, United Kingdom
Bristol Royal Infirmary
Bristol, England, BS2 8HW, United Kingdom
Broomfield Hospital
Broomfield, England, CM1 7ET, United Kingdom
Burnley General Hospital
Burnley, England, BB10 2PQ, United Kingdom
Queen's Hospital
Burton-on-Trent, England, DE13 0RB, United Kingdom
Addenbrooke's Hospital
Cambridge, England, CB2 2QQ, United Kingdom
Kent and Canterbury Hospital
Canterbury, England, CT1 3NG, United Kingdom
St. Helier Hospital
Carshalton, England, SM5 1AA, United Kingdom
Countess of Chester Hospital
Chester, England, CH2 1UL, United Kingdom
Colchester General Hospital
Colchester, England, CO4 5JL, United Kingdom
Castle Hill Hospital
Cottingham, England, HU16 5JQ, United Kingdom
Walsgrave Hospital
Coventry, England, CV2 2DX, United Kingdom
Mid Cheshire Hospitals Trust- Leighton Hopsital
Crewe, England, CW1 4QJ, United Kingdom
Mayday University Hospital
Croydon, England, United Kingdom
Darent Valley Hospital
Dartford Kent, England, DA2 8DA, United Kingdom
Derbyshire Royal Infirmary
Derby, England, DE1 2QY, United Kingdom
Royal Derby Hospital
Derby, England, DE22 3NE, United Kingdom
Dorset County Hospital
Dorchester, England, DT1 2JY, United Kingdom
Russells Hall Hospital
Dudley, England, DY1 2HQ, United Kingdom
Eastbourne District General Hospital
Eastbourne, England, BN21 2UD, United Kingdom
Birmingham Women's Hospital
Edgbaston, England, B15 2TG, United Kingdom
Epsom General Hospital
Epsom, Surrey, England, KT18 7EG, United Kingdom
Royal Devon and Exeter Hospital
Exeter, England, EX2 5DW, United Kingdom
Royal Bolton Hospital
Farnworth, England, BL4 0JR, United Kingdom
Frimley Park Hospital
Frimley, England, GU16 7UJ, United Kingdom
Grantham and District Hospital
Grantham, Lincolnshire, England, NG31 8DG, United Kingdom
Diana Princess of Wales Hospital
Grimsby, England, DN33 2BA, United Kingdom
Harrogate District Hospital
Harrogate, England, HG2 7SX, United Kingdom
Wycombe General Hospital
High Wycombe, England, United Kingdom
Princess Royal Hospital at Hull and East Yorkshire NHS Trust
Hull, England, HU8 9HE, United Kingdom
Ipswich Hospital
Ipswich, England, IP4 5PD, United Kingdom
Kidderminster Hospital
Kidderminster Worcestershire, England, DY11 6RJ, United Kingdom
Royal Albert Edward Infirmary
Lancanshire, England, WN1 2NN, United Kingdom
Royal Lancaster Infirmary
Lancaster, England, LA1 4RP, United Kingdom
Leeds General Infirmary
Leeds, England, LS1 3EX, United Kingdom
Cookridge Hospital
Leeds, England, LS16 6QB, United Kingdom
Leeds Cancer Centre at St. James's University Hospital
Leeds, England, LS9 7TF, United Kingdom
Leicester Royal Infirmary
Leicester, England, LE1 5WW, United Kingdom
Leicester General Hospital
Leicester, England, LE5 4PW, United Kingdom
Lincoln County Hospital
Lincoln, England, LN2 5QY, United Kingdom
Royal Liverpool University Hospital
Liverpool, England, L7 8XP, United Kingdom
Royal London Hospital
London, England, E1 1BB, United Kingdom
Whipps Cross Hospital
London, England, E11 1NR, United Kingdom
Saint Bartholomew's Hospital
London, England, EC1A 7BE, United Kingdom
Guy's Hospital
London, England, SE1 9RT, United Kingdom
Hammersmith Hospital
London, England, W12 OHS, United Kingdom
Middlesex Hospital
London, England, W1T 3AA, United Kingdom
St. Mary's Hospital
London, England, W2 1NY, United Kingdom
Charing Cross Hospital
London, England, W6 8RF, United Kingdom
Macclesfield District General Hospital
Macclesfield, England, SK10 3BL, United Kingdom
Maidstone Hospital
Maidstone, England, ME16 9QQ, United Kingdom
Christie Hospital
Manchester, England, M20 4BX, United Kingdom
Clatterbridge Centre for Oncology
Merseyside, England, CH63 4JY, United Kingdom
James Cook University Hospital
Middlesbrough, England, TS4 3BW, United Kingdom
Milton Keynes General Hospital
Milton Keynes, England, MK6 5LD, United Kingdom
Newcastle Upon Tyne Hospitals NHS Trust
Newcastle upon Tyne, England, NE7 7DN, United Kingdom
Mount Vernon Cancer Centre at Mount Vernon Hospital
Northwood, England, HA6 2RN, United Kingdom
Norfolk and Norwich University Hospital
Norwich, England, NR4 7UY, United Kingdom
Nottingham City Hospital
Nottingham, England, NG5 1PB, United Kingdom
Kings Mill Hospital
Nottinghamshire, England, NG17 4JL, United Kingdom
George Eliot Hospital
Nuneaton, England, CV10 7DJ, United Kingdom
Churchill Hospital
Oxford, England, OX3 7LJ, United Kingdom
Peterborough Hospitals Trust
Peterborough, England, PE3 6DA, United Kingdom
Derriford Hospital
Plymouth, England, PL6 8DH, United Kingdom
Dorset Cancer Centre
Poole Dorset, England, BH15 2JB, United Kingdom
Rosemere Cancer Centre at Royal Preston Hospital
Preston, England, PR2 9HT, United Kingdom
Berkshire Cancer Centre at Royal Berkshire Hospital
Reading, England, RG1 5AN, United Kingdom
Alexandra Healthcare NHS
Redditch, Worcestershire, England, B98 7UB, United Kingdom
Queens Hospital
Romford, England, RM3 0BE, United Kingdom
Conquest Hospital
Saint Leonards-on-Sea, England, TN37 7RD, United Kingdom
Hope Hospital
Salford, England, M6 8HD, United Kingdom
Salisbury District Hospital
Salisbury, England, SP2 8BJ, United Kingdom
Scarborough General Hospital
Scarborough, England, YO12 6QL, United Kingdom
Scunthorpe General Hospital
Scunthorpe, England, DN15 7BH, United Kingdom
Royal Shrewsbury Hospital
Shrewsbury, England, SY3 8XQ, United Kingdom
Wexham Park Hospital
Slough, Berkshire, England, SL2 4HL, United Kingdom
Solihull Hospital
Solihull, England, B91 2JL, United Kingdom
Southampton General Hospital
Southampton, England, SO16 6YD, United Kingdom
Southport and Formby District General Hospital
Southport, England, PR8 6PN, United Kingdom
Staffordshire General Hospital
Stafford, England, ST16 3SA, United Kingdom
Lister Hospital
Stevenage, England, SG1 4AB, United Kingdom
Stirling Royal Infirmary
Stirling, England, FK8 2AU, United Kingdom
Stepping Hill Hospital
Stockport, England, SK2 7JE, United Kingdom
Kingston Hospital
Surrey, England, KT2 7QB, United Kingdom
East Surrey Hospital
Surrey, England, RH1 5RH, United Kingdom
Royal Marsden - Surrey
Sutton, England, SM2 5PT, United Kingdom
Great Western Hospital
Swindon, England, SN3 6BB, United Kingdom
Taunton and Somerset Hospital
Taunton, England, TA1 5DA, United Kingdom
Torbay Hospital
Torquay, England, TQ2 7AA, United Kingdom
Hillingdon Hospital
Uxbridge, England, UB8 3NN, United Kingdom
Warwick Hospital
Warwick, England, CV34 5BW, United Kingdom
Sandwell General Hospital
West Bromwich, England, B71 4HJ, United Kingdom
Southend University Hospital NHS Foundation Trust
Westcliff-on-Sea, England, SS0 0RY, United Kingdom
New Cross Hospital
Wolverhampton, England, WV10 0QP, United Kingdom
Worthing Hospital
Worthing, England, BN11 2DH, United Kingdom
Yeovil District Hospital
Yeovil, England, BA21 4AT, United Kingdom
Cancer Care Centre at York Hospital
York, England, Y031 8HE, United Kingdom
Belfast City Hospital Trust Incorporating Belvoir Park Hospital
Belfast, Northern Ireland, BT8 8JR, United Kingdom
Downe Hospital
Downpatrick, Northern Ireland, BT30 6JA, United Kingdom
Altnagelvin Area Hospital
Londonderry, Northern Ireland, BT47 1SB, United Kingdom
Craigavon Area Hospital
Portadown, Craigavon, Northern Ireland, BT63 5QQ, United Kingdom
Aberdeen Royal Infirmary
Aberdeen, Scotland, AB25 2ZN, United Kingdom
Ayr Hospital
Ayr, Scotland, KA6 6DX, United Kingdom
Falkirk and District Royal Infirmary
Falkirk, Scotland, FK1 5QE, United Kingdom
Western Infirmary
Glasgow, Scotland, G11 6NT, United Kingdom
Pinderfields General Hospital
Wakefield, Scotland, WF1 4DG, United Kingdom
Princess of Wales Hospital
Bridgend, Wales, CF31 1JP, United Kingdom
Velindre Cancer Center at Velindre Hospital
Cardiff, Wales, CF14 2TL, United Kingdom
University Hospital of Wales
Cardiff, Wales, CF14 4XW, United Kingdom
Royal Gwent Hospital
Newport Gwent, Wales, NP9 2UB, United Kingdom
Glan Clwyd Hospital
Rhyl, Denbighshire, Wales, LL 18 5UJ, United Kingdom
Singleton Hospital
Swansea, Wales, SA2 8QA, United Kingdom
Queen Victoria Hospital
Morecambe, LA4 5NN, United Kingdom
Edith Cavell Hospital
Peterborough, PE3 9GZ, United Kingdom
Southlands Hospital
Shoreham-by-Sea, BN43 6TQ, United Kingdom
Princess Anne Hospital
Southampton, SO16 5YA, United Kingdom
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Rosalind Eeles, PhD, FRCR, FRCP, FMed Sci
Royal Marsden NHS Foundation Trust
Study Design
- Study Type
- observational
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
August 13, 2009
First Posted
August 14, 2009
Study Start
June 1, 1993
Last Updated
August 26, 2013
Record last verified: 2009-08