NCT00899184

Brief Summary

RATIONALE: Collecting and storing samples of blood from patients and their brothers with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer. PURPOSE: This laboratory study is looking at changes in DNA in patients and their brothers with prostate cancer.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
646

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2006

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 23, 2006

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 30, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 30, 2007

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

May 9, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 12, 2009

Completed
Last Updated

May 19, 2017

Status Verified

May 1, 2017

Enrollment Period

1 year

First QC Date

May 9, 2009

Last Update Submit

May 17, 2017

Conditions

Prostate Cancer

Keywords

recurrent prostate cancerstage IV prostate cancerstage I prostate cancerstage IIB prostate cancerstage IIA prostate cancerstage III prostate cancer

Outcome Measures

Primary Outcomes (2)

  • Frequency of single nucleotide polymorphism (SNP) genotypes

    1 month

  • Age of onset of prostate cancer in patients and their affected siblings

    1 month

Interventions

polymorphism analysisGENETIC
laboratory biomarker analysisOTHER

Eligibility Criteria

Age18 Years - 120 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
DISEASE CHARACTERISTICS: * Meets one of the following criteria: * Patient or sibling diagnosed with prostate cancer * Cancer-free participant (healthy control) * Whole blood sample available PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

MeSH Terms

Conditions

Prostatic Neoplasms

Interventions

Amplified Fragment Length Polymorphism Analysis

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

DNA FingerprintingGenetic TechniquesInvestigative TechniquesPolymerase Chain ReactionNucleic Acid Amplification Techniques

Study Officials

  • Kim M. Hirshfield, MD, PhD

    Rutgers Cancer Institute of New Jersey

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 9, 2009

First Posted

May 12, 2009

Study Start

May 23, 2006

Primary Completion

May 30, 2007

Study Completion

May 30, 2007

Last Updated

May 19, 2017

Record last verified: 2017-05