Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

NCT00952835 | Unknown

• 1 other identifier: AOV-1716
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

In this study will be consecutive enrolled children with asthma (classified according to GINA guidelines) and rhinitis (classified by ARIA guidelines); the investigators will research clinical personal and parental history regarding allergic diseases, exposition to passive smoking and interpretate hematochemical parameters markers of atopy. Skin Prick Tests will be performed. In this study the investigators will evaluate lung function parameters (spirometry with bronchial reversibility test and exercise induced bronchoconstriction, oscillometry, respiratory plethysmography, etc.), airway inflammatory indices such as exhaled nitric oxide at different flows, exhaled and nasal temperature, nasal cytology. The aim of the study will be to evaluate possible correlation between these different parameters and clinical status of the patients.

Conditions

Asthma; Rhinitis

Keywords

Asthma; rhinitis; EIB; Exhaled Nitric oxide; lung function; vitamin d

Outcome Measures

Primary Outcomes (1)

• Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

  Evaluation of Different Disease Control Indices in Children With Asthma and Rhinitis

Study Arms (1)

asthma and rhinitis control

Other: regular treatment

Interventions

regular treatment OTHER

regular treatment

Also known as: asthma treatment

asthma and rhinitis control

Eligibility Criteria

• Age: 5 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

children with asthma and/or rhinitis visited at the outpatients clinic at the University of Verona will be invited to participate to the study

You may qualify if:

• patient with asthma and rhinitis

You may not qualify if:

• age \<5 years
• chronic respiratory diseases

Sponsors & Collaborators

• Universita di Verona: lead
• Azienda Ospedaliera Universitaria Policlinico: collaborator

Study Sites (1)

Pediatric department University of Verona

Verona, Verona, 37134, Italy

RECRUITING

Related Publications (2)

• Chinellato I, Piazza M, Peroni D, Sandri M, Chiorazzo F, Boner AL, Piacentini G. Bronchial and alveolar nitric oxide in exercise-induced bronchoconstriction in asthmatic children. Clin Exp Allergy. 2012 Aug;42(8):1190-6. doi: 10.1111/j.1365-2222.2012.03973.x.

  PMID: 22805466 DERIVED

• Peroni DG, Cattazzo E, Chinellato I, Piazza M, Tezza G, Boner AL, Piacentini GL. Nasal mucosa temperature as a marker of disease in children with allergic rhinitis. Am J Rhinol Allergy. 2012 Jul-Aug;26(4):e115-8. doi: 10.2500/ajra.2012.26.3803.

  PMID: 22801008 DERIVED

MeSH Terms

Conditions

Asthma; Rhinitis

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Respiratory Tract Infections; Infections; Nose Diseases; Otorhinolaryngologic Diseases

Study Officials

• Attilio Boner, MD

  Universita di Verona

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Attilio Boner, MD

CONTACT

--390458124615; attilio.boner@univr.it

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: full professor

Study Record Dates

• First Submitted: August 3, 2009
• First Posted: August 6, 2009
• Study Start: July 1, 2009
• Primary Completion: December 1, 2013
• Study Completion: December 1, 2014
• Last Updated: June 19, 2013

Record last verified: 2013-06

Locations

IT (1)