Screening Scottish Swimmers for Asthma and Rhinitis

NCT00831428 | Completed Results

• 1 other identifier: CLE004
• Study Type: observational
• Target: 97
• Locations: 1 country
• Sites: 1

Brief Summary

The Scottish National and District swimming teams will be screened for asthma and rhinitis using both mannitol challenge and sport-based exercise challenge.

Conditions

Asthma; Rhinitis

Keywords

asthma; rhinitis; swimmers; mannitol

Outcome Measures

Primary Outcomes (1)

• Tidal Nitric Oxide

  This test will be performed prior to entering the pool, and on exiting the pool

Secondary Outcomes (5)

• Mannitol Challenge

  This test will be performed once on a district and once on a national squad training day

• Sport-based Challenge

  This test will be performed once on a district and once on a national squad training day

• Nasal Nitric Oxide

  This test will be performed prior to entering the pool, and on exiting the pool

• Skin Prick Test

  This test will be performed once on a district and once on a national squad training day

• Mini Nasal Lavage

  This test will be performed prior to entering the pool, and on exiting the pool

Study Arms (1)

Scottish swimming team

Other: no intervention

Interventions

no intervention OTHER

this is a screening study, not an interventional study

Scottish swimming team

Eligibility Criteria

• Age: 11 Years - 23 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The Scottish national and district swimming teams

You may qualify if:

• member of the Scottish national and district swimming team
• informed consent obtained

You may not qualify if:

• pregnant, lactating or planning to become pregnant
• concomitant use of medicines (prescribed, over-the-counter or herbal) that may interfere with the trial.
• any clinically significant medical condition, as deemed by the clinical investigators, which may endanger the health of the participant or jeopardise the protocol.
• inability to comply with the protocol.

Sponsors & Collaborators

• Brian J Lipworth: lead

Study Sites (1)

The national swimming academy in Stirling

Stirling, Stirlingshire, FK9 4LA, United Kingdom

Location

Related Publications (1)

• Clearie KL, Williamson PA, Vaidyanathan S, Short P, Goudie A, Burns P, Hopkinson P, Meldrum K, Howaniec L, Lipworth BJ. Disconnect between standardized field-based testing and mannitol challenge in Scottish elite swimmers. Clin Exp Allergy. 2010 May;40(5):731-7. doi: 10.1111/j.1365-2222.2010.03461.x. Epub 2010 Mar 1.

  PMID: 20214665 RESULT

MeSH Terms

Conditions

Asthma; Rhinitis

Condition Hierarchy (Ancestors)

Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Respiratory Hypersensitivity; Hypersensitivity, Immediate; Hypersensitivity; Immune System Diseases; Respiratory Tract Infections; Infections; Nose Diseases; Otorhinolaryngologic Diseases

Results Point of Contact

• Title: Dr Karine Clearie
• Organization: University of Dundee

k.clearie@dundee.ac.uk

01382 496440

Study Officials

• Karine L Clearie, MBBS, MRCP

  Asthma and Allergy Research Group

  PRINCIPAL INVESTIGATOR

• Brian J Lipworth, MBchB

  Asthma and Allergy Research Group

  STUDY DIRECTOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Professor (Clinical) Airway allergy and COPD

Study Record Dates

• First Submitted: January 28, 2009
• First Posted: January 29, 2009
• Study Start: February 1, 2009
• Primary Completion: May 1, 2009
• Study Completion: June 1, 2009
• Last Updated: April 24, 2019
• Results First Posted: September 23, 2011

Record last verified: 2019-04

Locations

GB (1)