NCT00949000

Brief Summary

The objective of the study is to collect information on the naturally occurring variations in ST deviations at different heart rates, as detected by the AnalyST and AnalyST Accel Implantable Cardioverter Defibrillators (ICD).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2009

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2009

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

July 29, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

July 30, 2009

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2011

Completed
Last Updated

February 4, 2019

Status Verified

February 1, 2019

Enrollment Period

1.6 years

First QC Date

July 29, 2009

Last Update Submit

February 1, 2019

Conditions

Outcome Measures

Primary Outcomes (4)

  • Evaluation of start and duration of isoelectric PR intervals

    4 weeks

  • Evaluation of start and duration of ST intervals

    4 weeks

  • Evaluation of ST segment deviations during stress testing across the 4 heart rate zones defined by the device

    4 weeks

  • Incidence of ischemic events detected based on the external ECG

    4 weeks

Study Arms (1)

ICD Implant

OTHER

Implantation of a commercially available AnalyST or AnalyST Accel ICD

Device: ICD Implantation

Interventions

Implantation of a commercially available AnalyST or AnalyST Accel ICD

ICD Implant

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patient has received or is scheduled to receive a St Jude Medical AnalyST or AnalyST Accel ICD;
  • Patient has documented ischemic heart disease.

You may not qualify if:

  • Patient has an indication for ventricular pacing;
  • Patient has chronotropic incompetence or insufficiency;
  • Patient has a contraindication to stress testing;
  • Patient is physically unable to complete the stress test protocol;
  • The patient has persistent or permanent atrial fibrillation (AF);
  • Patient is unable to comply with the protocol and follow-up schedule based on geographic location or for any reason;
  • Patient is pregnant;
  • Patient is minor (\< 18 years old).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Klinikum Coburg

Coburg, Bavaria, 96450, Germany

Location

Kerckhoff-Klinik

Bad Nauheim, Hesse, 61321, Germany

Location

Medizinische Einrichtungen der RWTH Aachen

Aachen, N. Rhin, 52074, Germany

Location

Klinikum der Stadt Ludwigshafen am Rhein

Ludwigshafen, N. Rhin, 67063, Germany

Location

Klinikum Luedenscheid

Lüdenscheid, N. Rhin, 58515, Germany

Location

MeSH Terms

Conditions

Myocardial Ischemia

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Christian Hamm, Prof. Dr.

    Kerckhoff-Klinik, Bad Nauheim, Germany

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

July 29, 2009

First Posted

July 30, 2009

Study Start

July 1, 2009

Primary Completion

February 1, 2011

Study Completion

February 1, 2011

Last Updated

February 4, 2019

Record last verified: 2019-02

Locations