NCT00945022

Brief Summary

Following waking up from surgery performed under general anesthesia, patients are suffering from discomforting oral dryness, and moreover, they are not allowed drinking for 24 hours. The current management involves the wetting of patient's lips using wet bandage. This action is dependent on the presence of a family member or a nurse, which is not always possible. Many patients describe the oral dryness as a suffering, added to the suffering anyway entailed by surgery. The investigated Lipsus device is intended for oral wetting, relieving patient's suffering and minimizing the dependence on continuous presence next to patient's bed.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Oct 2011

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 13, 2009

Completed
10 days until next milestone

First Posted

Study publicly available on registry

July 23, 2009

Completed
2.2 years until next milestone

Study Start

First participant enrolled

October 1, 2011

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2012

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2012

Completed
Last Updated

June 9, 2011

Status Verified

July 1, 2009

Enrollment Period

4 months

First QC Date

July 13, 2009

Last Update Submit

June 8, 2011

Conditions

Keywords

General Surgery

Outcome Measures

Primary Outcomes (1)

  • The safety of using the Lipsus device for oral wetting will be established by physician's assessment/observation of adverse events (signs of pain, allergies, infection or any adverse effect).

    2 days

Secondary Outcomes (1)

  • The efficacy of using the Lipsus device for oral wetting will be established by Level of oral dryness improvement measured by VAS oral dryness questionnaire.

    2 days

Study Arms (1)

Lipsus

EXPERIMENTAL
Device: wetting lips following surgery using anesthesia

Interventions

The investigator will position the Lipsus device in accordance with the instructions for use

Lipsus

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is scheduled for surgery under general anesthesia.
  • Male/female age 18 and up.
  • Subject able to comprehend and give informed consent for participation in this study
  • Subject must sign the Informed Consent Form.

You may not qualify if:

  • Subjects who have any form of suspicious lesion in treatment target area.
  • Pregnant or lactating Subjects
  • Subjects with any infection / abscess / bleeding / blister / crack / edema / fissure / ulcer / pain in treatment target area.
  • Eczema or dermatitis in treatment target area
  • Subjects on drugs or psychologically determined unsuitable for the study.
  • Subject is suffering extreme general weakness.
  • Subject objects to the study protocol.
  • Concurrent participation in any other clinical study
  • Physician objection

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Shaari Zedek Medical Center

Jerusalem, Israel

Location

MeSH Terms

Conditions

Xerostomia

Condition Hierarchy (Ancestors)

Salivary Gland DiseasesMouth DiseasesStomatognathic Diseases

Study Officials

  • Alexander Yuskavitch, Dr.

    Shaari Zedek Medical Center, Jerusalem

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

July 13, 2009

First Posted

July 23, 2009

Study Start

October 1, 2011

Primary Completion

February 1, 2012

Study Completion

April 1, 2012

Last Updated

June 9, 2011

Record last verified: 2009-07

Locations