Reduction of the Glycemic Index by a Novel Viscous Polysaccharide
Effect of Adding the Novel Fiber, PGX®,to Commonly Consumed Foods on Glycemic Response and Glycemic Index: A Practical and Effective Strategy for Reducing Post Prandial Blood Glucose Levels.
1 other identifier
interventional
10
1 country
1
Brief Summary
Reductions of postprandial glucose levels have been demonstrated previously with the addition of a novel viscous polysaccharide (NVP) to a glucose drink and standard white bread. This study explores whether these reductions are sustained when NVP is added to a range of commonly consumed foods.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_2
Started May 2006
Shorter than P25 for phase_2
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2006
CompletedFirst Submitted
Initial submission to the registry
March 25, 2009
CompletedFirst Posted
Study publicly available on registry
July 9, 2009
CompletedJuly 9, 2009
July 1, 2009
1 month
March 25, 2009
July 8, 2009
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Relative Blood glucose response of food with and without NVP
Acute blood glucose response measured at 0, 15,30,45,60,90 and 120 min
Study Arms (15)
1
PLACEBO COMPARATORControl White bread containing 50g available carbohydrate
2
PLACEBO COMPARATORWhite bread and milk control
3
PLACEBO COMPARATORGranola control
4
PLACEBO COMPARATORCornflakes and milk control
5
PLACEBO COMPARATORWhite rice control
6
PLACEBO COMPARATORFruit yogurt control
7
PLACEBO COMPARATORTurkey dinner control
8
EXPERIMENTALGranola
9
EXPERIMENTALCornflakes and milk
10
EXPERIMENTALWhite Rice
11
EXPERIMENTALFruit yogurt
12
EXPERIMENTALTurkey dinner
13
PLACEBO COMPARATORWhite Bread
14
PLACEBO COMPARATORWhite bread
15
EXPERIMENTALGranola
Interventions
Eligibility Criteria
You may qualify if:
- healthy individuals
- years old
- BMI less than 35 kg/m2
You may not qualify if:
- Medications influencing gastrointestinal function
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Glycemic Index Laboratories, Inclead
- InovoBiologic Inc.collaborator
- Canadian Center for Functional Medicinecollaborator
Study Sites (1)
Glycemic Index Laboratories, Inc.
Toronto, Ontario, Canada
Related Publications (1)
Jenkins AL, Kacinik V, Lyon M, Wolever TM. Effect of adding the novel fiber, PGX(R), to commonly consumed foods on glycemic response, glycemic index and GRIP: a simple and effective strategy for reducing post prandial blood glucose levels--a randomized, controlled trial. Nutr J. 2010 Nov 22;9:58. doi: 10.1186/1475-2891-9-58.
PMID: 21092221DERIVED
MeSH Terms
Interventions
Study Officials
- STUDY DIRECTOR
Alexandra L Jenkins, PhD, RD
Glycemic Index Laboratories, Inc
- PRINCIPAL INVESTIGATOR
Thomas MS Wolever, MD
Glycemic Index Laboratories, Inc
Study Design
- Study Type
- interventional
- Phase
- phase 2
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- INDUSTRY
Study Record Dates
First Submitted
March 25, 2009
First Posted
July 9, 2009
Study Start
May 1, 2006
Primary Completion
June 1, 2006
Study Completion
August 1, 2006
Last Updated
July 9, 2009
Record last verified: 2009-07