NCT00917085

Brief Summary

To see if infant outcomes will improve when mothers are helped to hold their preterm infants skin-to-skin as soon as possible after birth and as often as possible and for as long as possible each time during the next five days.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Jul 1996

Longer than P75 for phase_1

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 1996

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2001

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2001

Completed
7.5 years until next milestone

First Submitted

Initial submission to the registry

June 8, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 10, 2009

Completed
Last Updated

August 10, 2009

Status Verified

August 1, 2009

Enrollment Period

5.4 years

First QC Date

June 8, 2009

Last Update Submit

August 7, 2009

Conditions

Keywords

Preterm infantSkin-to-skin contactkangaroo caretemperaturebehavioral state

Outcome Measures

Primary Outcomes (1)

  • Infant Temperature

    A total of 60 measrements for each outcome beginning at birth once every 15 minutes and gradually decreasing in frequency to once every 6 hours by Day 5.

Secondary Outcomes (1)

  • Infant Behavioral State

    A total of 60 measrements for each outcome beginning at birth once every 15 minutes and gradually decreasing in frequency to once every 6 hours by Day 5.

Study Arms (2)

Control group

NO INTERVENTION

Control infants received the same standard care as infants who were not in the study. Infants were kept warm in incubators or warmer beds and were wrapped in blankets when held by their mothers. Hospital staff was responsible for providing standard care.

Skin-to-Skin group

EXPERIMENTAL
Behavioral: Skin-to-Skin contact

Interventions

Infants in the Skin-to-Skin group also had standard care provided by hospital staff. In addition, the researchers facilitated skin-to-skin contact by placing diaper-clad infants prone between their mothers' breasts as soon as possible after birth. Thereafter the infants and their mothers experienced skin-to-skin contact as often as possible and for as long as possible each time throughout the protocol.

Also known as: Kangaroo Care
Skin-to-Skin group

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Mother and Infant Dyads
  • Infants:
  • singleton birth
  • to 36 completed weeks
  • minute Apgar score of 6 or more
  • weighed 1300 to 3000 grams
  • no birth defects that would interfere with feeding
  • healthy enough to experience skin-to-skin contact with their mothers.
  • Mothers:
  • or more years of age
  • spoke English
  • free of serious drug abuse
  • well enough to experience skin-to-skin contact with their infants with assistance if needed.

You may not qualify if:

  • Infants:
  • too ill to be with their mothers
  • who have a condition that interferes with feeding.
  • Mothers:
  • who are too ill to care for their infant
  • are serious drug abusers.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

University Hospitals Case Medical Center

Cleveland, Ohio, United States

Location

Kadlec Medical Center

Richmond, Washington, United States

Location

Related Publications (7)

  • Moran M, Radzyminski SG, Higgins KR, Dowling DA, Miller MJ, Anderson GC. Maternal kangaroo (skin-to-skin) care in the NICU beginning 4 hours postbirth. MCN Am J Matern Child Nurs. 1999 Mar-Apr;24(2):74-9. doi: 10.1097/00005721-199903000-00006.

    PMID: 10083783BACKGROUND
  • Anderson GC, Dombrowski MA, Swinth JY. Kangaroo care: not just for stable preemies anymore. Reflect Nurs Leadersh. 2001;27(2):32-4, 45. No abstract available.

    PMID: 11987376BACKGROUND
  • Dombrowski MA, Anderson GC, Santori C, Burkhammer M. Kangaroo (skin-to-skin) care with a postpartum woman who felt depressed. MCN Am J Matern Child Nurs. 2001 Jul-Aug;26(4):214-6. doi: 10.1097/00005721-200107000-00012.

    PMID: 11452667BACKGROUND
  • Anderson GC, Chiu SH, Dombrowski MA, Swinth JY, Albert JM, Wada N. Mother-newborn contact in a randomized trial of kangaroo (skin-to-skin) care. J Obstet Gynecol Neonatal Nurs. 2003 Sep-Oct;32(5):604-11. doi: 10.1177/0884217503256616.

    PMID: 14565739BACKGROUND
  • Swinth JY, Anderson GC, Hadeed AJ. Kangaroo (skin-to-skin) care with a preterm infant before, during, and after mechanical ventilation. Neonatal Netw. 2003 Nov-Dec;22(6):33-8. doi: 10.1891/0730-0832.22.6.33.

    PMID: 14700180BACKGROUND
  • Hake-Brooks SJ, Anderson GC. Kangaroo care and breastfeeding of mother-preterm infant dyads 0-18 months: a randomized, controlled trial. Neonatal Netw. 2008 May-Jun;27(3):151-9. doi: 10.1891/0730-0832.27.3.151.

    PMID: 18557262BACKGROUND
  • Chiu SH, Anderson GC. Effect of early skin-to-skin contact on mother-preterm infant interaction through 18 months: randomized controlled trial. Int J Nurs Stud. 2009 Sep;46(9):1168-80. doi: 10.1016/j.ijnurstu.2009.03.005. Epub 2009 Apr 10.

    PMID: 19361802BACKGROUND

MeSH Terms

Conditions

Premature Birth

Interventions

Kangaroo-Mother Care Method

Condition Hierarchy (Ancestors)

Obstetric Labor, PrematureObstetric Labor ComplicationsPregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Intervention Hierarchy (Ancestors)

Patient PositioningPatient CareTherapeuticsInfant CareChild CareHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Gene C Anderson, PhD, RN, FAAN

    Case Western Reserve University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
NIH

Study Record Dates

First Submitted

June 8, 2009

First Posted

June 10, 2009

Study Start

July 1, 1996

Primary Completion

December 1, 2001

Study Completion

December 1, 2001

Last Updated

August 10, 2009

Record last verified: 2009-08

Locations