NCT00899873

Brief Summary

RATIONALE: Studying samples of cells in the laboratory from patients with cancer may help identify biomarkers related to cancer. It may also help doctors learn how patients respond to treatment. PURPOSE: This laboratory study is analyzing samples of cells from patients with chronic lymphocytic leukemia who were treated on clinical trial ECOG-2997.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
225

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2012

Shorter than P25 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 9, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 12, 2009

Completed
2.9 years until next milestone

Study Start

First participant enrolled

April 17, 2012

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 17, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 17, 2012

Completed
Last Updated

May 17, 2017

Status Verified

May 1, 2017

Enrollment Period

3 months

First QC Date

May 9, 2009

Last Update Submit

May 16, 2017

Conditions

Leukemia

Keywords

chronic lymphocytic leukemia

Outcome Measures

Primary Outcomes (1)

  • Correlation of biomarker analysis and correlation with outcome response

    1 month

Interventions

cytogenetic analysisGENETIC
flow cytometryOTHER
fluorescence activated cell sortingOTHER
immunoenzyme techniqueOTHER
laboratory biomarker analysisOTHER

Eligibility Criteria

Age18 Years - 120 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Samples submitted for research from patients enrolled on E2997

DISEASE CHARACTERISTICS: * Stored frozen viable cells from patients with chronic lymphocytic leukemia treated on clinical trial ECOG-2997 PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * Not specified

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

MeSH Terms

Conditions

LeukemiaLeukemia, Lymphocytic, Chronic, B-Cell

Interventions

Cytogenetic AnalysisFlow CytometryImmunoenzyme Techniques

Condition Hierarchy (Ancestors)

Neoplasms by Histologic TypeNeoplasmsHematologic DiseasesHemic and Lymphatic DiseasesLeukemia, B-CellLeukemia, LymphoidLymphoproliferative DisordersLymphatic DiseasesImmunoproliferative DisordersImmune System DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Cytological TechniquesClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisInvestigative TechniquesGenetic TechniquesCell SeparationCytophotometryFluorometryLuminescent MeasurementsPhotometryChemistry Techniques, AnalyticalImmunoassayImmunologic TechniquesImmunohistochemistryMolecular Probe Techniques

Study Officials

  • David Kaplan, MD, PhD

    University Hospitals Seidman Cancer Center

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
NETWORK
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 9, 2009

First Posted

May 12, 2009

Study Start

April 17, 2012

Primary Completion

July 17, 2012

Study Completion

July 17, 2012

Last Updated

May 17, 2017

Record last verified: 2017-05