NCT00897741

Brief Summary

RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer. PURPOSE: This laboratory study uses gene expression profiling to compare primary tumor cells with metastatic tumor cells in patients with metastatic pancreatic cancer.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2004

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2004

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2008

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2009

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 9, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 12, 2009

Completed
Last Updated

February 11, 2014

Status Verified

February 1, 2014

Enrollment Period

3.4 years

First QC Date

May 9, 2009

Last Update Submit

February 10, 2014

Conditions

Pancreatic Cancer

Keywords

recurrent pancreatic cancerstage IV pancreatic cancer

Outcome Measures

Primary Outcomes (1)

  • Gene expression profiles

    at time of biopsy

Interventions

microarray analysisGENETIC
laboratory biomarker analysisOTHER

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Cancer clinic

DISEASE CHARACTERISTICS: * Diagnosis of pancreatic adenocarcinoma of exocrine origin * Metastatic disease * Fresh biopsy material available from primary site of disease and a metastatic focus, including liver, peritoneum, or lymph node PATIENT CHARACTERISTICS: * Not specified PRIOR CONCURRENT THERAPY: * No prior chemotherapy or radiotherapy for pancreatic cancer

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Barbara Ann Karmanos Cancer Institute

Detroit, Michigan, 48201, United States

Location

MeSH Terms

Conditions

Pancreatic Neoplasms

Interventions

Microarray Analysis

Condition Hierarchy (Ancestors)

Digestive System NeoplasmsNeoplasms by SiteNeoplasmsEndocrine Gland NeoplasmsDigestive System DiseasesPancreatic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

Microchip Analytical ProceduresInvestigative Techniques

Study Officials

  • Philip A. Philip, MD, PhD, FRCP

    Barbara Ann Karmanos Cancer Institute

    STUDY CHAIR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 9, 2009

First Posted

May 12, 2009

Study Start

December 1, 2004

Primary Completion

May 1, 2008

Study Completion

March 1, 2009

Last Updated

February 11, 2014

Record last verified: 2014-02

Locations

US(1)