Interscanner Variation in Musculoskeletal Computed Tomography (CT) Measures

NCT00896415 | Completed

• 2 other identifiers: Inter-scanner studyTLANG_Interscanner
• Study Type: observational
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

Maintaining strong muscles is important for the independence and quality of life in our older population. Strong muscles provide mobility and reduce the chance of falls that lead to injury. Many researchers are carrying out studies to examine different types of exercise and drug treatments to prevent loss of muscle strength in older people. Often, these research studies use x-ray computed tomography (CT) scans to measure the size and the amount of fat in different muscles. These factors are known to reflect muscle health. Large studies can involve many research subjects recruited at many different clinics with different CT scanners. To ensure that these studies provide reliable results, the investigators must have procedures to make sure that different CT scanners measure the same results for the same amount of fat or muscle. The goal of our study is to develop these procedures. In this project, the investigators will study women because they have the highest risk of bone fractures resulting from falls. Thus, the subjects are being asked to volunteer for a study where the subjects will be scanned on different scanners.

Conditions

Accidental Falls; Loss of Muscle Strength

Keywords

on two models of CT scanner acquire CT images of the abdomen pelvis and midthigh in 20 Postmenopausal female volunteers

Eligibility Criteria

• Age: 60 Years - 70 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

In this project we will study women 60-70 years old because they have the highest risk of bone fractures resulting from falls.

You may qualify if:

• age 60-70 years old
• healthy

You may not qualify if:

• no history of spine surgery
• no history of hip implantation or replacement
• no scoliosis or other spine deformity
• not using walking canes or wheelchair

Sponsors & Collaborators

• University of California, San Francisco: lead

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: May 8, 2009
• First Posted: May 11, 2009
• Study Start: May 1, 2009
• Study Completion: November 1, 2009
• Last Updated: June 29, 2010

Record last verified: 2009-05