NCT00894426

Brief Summary

The aim of this study is to assess the perception of chronic obstructive pulmonary disease (COPD) patients in symptoms related to morning activities. Also the researchers investigated how to describe the impact of symptoms on sleep quality and how to use the medication in Korea COPD treatments.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2009

Shorter than P25 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2009

Completed
3 days until next milestone

Study Start

First participant enrolled

May 1, 2009

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 7, 2009

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

December 3, 2010

Status Verified

December 1, 2010

First QC Date

April 28, 2009

Last Update Submit

December 2, 2010

Conditions

Keywords

COPDSymptomMorning activityQuestionnaire

Outcome Measures

Primary Outcomes (1)

  • To assess the perception of COPD Patients in symptoms related to morning activities

    At baseline and last visit (after 2~3 months)

Secondary Outcomes (3)

  • To assess the patient's perception of the variability of symptoms

    At baseline and last visit (after 2~3 months)

  • To describe how patients use their COPD treatments

    At baseline and last visit (after 2~3 months)

  • To investigate factors that may influence the patient's perception of symptom variability (such as patient characteristics, COPD treatments, co morbidities, etc…)

    At baseline and last visit (after 2~3 months)

Study Arms (2)

1

Morning Symptoms (+)

2

Morning Symptoms (-)

Eligibility Criteria

Age45 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The inclusion/exclusion criteria are designed to select subjects suffering from severe COPD (according to spirometric classification, GOLD stage III and IV) and in a stable state

You may qualify if:

  • COPD outpatients over 45 years old
  • Lung function: post-FEV1 \< 50%
  • Current or ex-smoker \> 10 packs per year
  • Patients who were not on medication of ISC/FC at least 2 weeks

You may not qualify if:

  • Ongoing exacerbation of COPD or within the previous 3 months
  • History of asthma or allergic rhinitis
  • Lung cancer or any other significant respiratory disease such as bronchiectasis, lung fibrosis, interstitial lung disease, tuberculosis, sarcoidosis
  • Current participation in an interventional clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Research Site

Daegu, South Korea

Location

Research Site

Gyongiju, South Korea

Location

Research Site

Pohang, South Korea

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Joonwoo Bahn

    Astrazenca Korea, Medical Department

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

April 28, 2009

First Posted

May 7, 2009

Study Start

May 1, 2009

Study Completion

December 1, 2009

Last Updated

December 3, 2010

Record last verified: 2010-12

Locations