Discard:Characterisation of Colonic Polyps in Vivo
DISCARD
Characterisation of Small Colonic Polyps in Vivo
1 other identifier
observational
130
1 country
1
Brief Summary
Prospective study of accuracy of colonic polyp characterisation in vivo using high resolution white light endoscopy, narrow band imaging and chromoendoscopy.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Aug 2008
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2008
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2009
CompletedFirst Submitted
Initial submission to the registry
April 27, 2009
CompletedFirst Posted
Study publicly available on registry
April 28, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2009
CompletedAugust 5, 2022
August 1, 2022
6 months
April 27, 2009
August 4, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Accuracy of polyp characterisation
12 months
Secondary Outcomes (1)
Change in surveillance interval after formal histopathology
12 months
Study Arms (4)
1
2
3
4
Eligibility Criteria
The study group therefore would comprise those presenting for 3 yearly follow up or sooner i.e. those with a resected colorectal cancer or those with ≥ three adenomas or one advanced ≥10mm adenoma or those with a positive faecal occult blood test
You may qualify if:
- Patients over 18 years of age, assessed as fit for routine colonoscopy
- Patients attending for screening or surveillance colonoscopy meeting the following criteria:
- Polyp surveillance with at least 3 adenomas or 1 adenoma\>10mm at previous colonoscopy
- Surveillance post colorectal cancer resection
- Screening with positive faecal occult blood test
You may not qualify if:
- Patients with known colitis or polyposis syndromes
- Unable or unwilling to give informed consent
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Wolfson Unit for Endoscopy, St Mark's Hospital
Harrow, Moddlesex, HA1 3UJ, United Kingdom
Related Publications (1)
Ignjatovic A, East JE, Suzuki N, Vance M, Guenther T, Saunders BP. Optical diagnosis of small colorectal polyps at routine colonoscopy (Detect InSpect ChAracterise Resect and Discard; DISCARD trial): a prospective cohort study. Lancet Oncol. 2009 Dec;10(12):1171-8. doi: 10.1016/S1470-2045(09)70329-8. Epub 2009 Nov 10.
PMID: 19910250DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Brian P Saunders, MD
Wolfson Unit for Endoscopy, St Mark's Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
April 27, 2009
First Posted
April 28, 2009
Study Start
August 1, 2008
Primary Completion
February 1, 2009
Study Completion
June 1, 2009
Last Updated
August 5, 2022
Record last verified: 2022-08