NCT00879580

Brief Summary

The purpose of this study is to evaluate the morbidity, mortality, and efficacy of use of the Enterprise(TM) stent for the treatment of (ruptured or non-ruptured) intracranial aneurysms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
133

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Feb 2009

Longer than P75 for all trials

Geographic Reach
1 country

14 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2009

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 31, 2009

Completed
10 days until next milestone

First Posted

Study publicly available on registry

April 10, 2009

Completed
4.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2013

Completed
Last Updated

October 11, 2013

Status Verified

October 1, 2013

Enrollment Period

4.5 years

First QC Date

March 31, 2009

Last Update Submit

October 10, 2013

Conditions

Keywords

aneurysmstentintracranial aneurysmRuptured Intracranial Aneurysm

Outcome Measures

Primary Outcomes (1)

  • Morbidity and Mortality

    Day 30 and 1 year post-procedure

Study Arms (2)

Non-ruptured aneurysms

Patients with intracranial aneurysm(s) requiring an endovascular treatment with a Codman ENTERPRISE stent who have one or more non-ruptured or late ruptured (\>30days), intracranial aneurysm.

Acute ruptured Aneurysms

Patients with intracranial aneurysm(s) requiring an endovascular treatment with a Codman ENTERPRISE stent who have a on or more acute ruptured (\<30Days) aneurysms

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects presenting with ruptured or non-ruptured aneurysms for whom simple or balloon-assisted endovascular treatment is considered impossible or insufficient by the interventional neuroradiologist.

You may qualify if:

  • Patient implanted with one or more CODMAN ENTERPRISE™ stents and who present one or more ruptured or non-ruptured intracranial aneurysms assessed by angiography
  • Agreement to take part in the study by the patient, or a representative of the patient in case of patient inability, after being informed by the investigator and have received information letter.

You may not qualify if:

  • Minors \<18 years of age
  • Patient implanted for the same aneurysm with a CODMAN ENTERPRISE™ stent in association with one or more stents from a different brand.
  • Patient who does not accept to take part in the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (14)

CHU Amiens

Amiens, 80054, France

Location

Jean Minjoz Hospital

Besançon, 25030, France

Location

Pellegrin Hospital

Bordeaux, 33076, France

Location

Albert Michallon Hospital

Grenoble, 38043, France

Location

Roger Salengro Hospital

Lille, 59037, France

Location

Timone Hospital

Marseille, 13005, France

Location

Lariboisiere Hospital

Paris, 75010, France

Location

La Pitie Salpetiere Hospital

Paris, 75561, France

Location

Pitie Salpetriere Hospital

Paris, 75561, France

Location

La Pitie Salpetriere Hospital

Paris, 75651, France

Location

Rothschild Foundation

Paris, 75940, France

Location

Beaujon Hospital

Paris, 92118, France

Location

White House Hospital

Reims, 51092, France

Location

Purpan Hospital

Toulouse, 31059, France

Location

MeSH Terms

Conditions

Intracranial AneurysmAneurysm

Condition Hierarchy (Ancestors)

Intracranial Arterial DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Jonathan Megerian, MD, PhD

    Codman & Shurtleff

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 31, 2009

First Posted

April 10, 2009

Study Start

February 1, 2009

Primary Completion

August 1, 2013

Study Completion

August 1, 2013

Last Updated

October 11, 2013

Record last verified: 2013-10

Locations