A Cluster Randomized Trial to Evaluate Long Lasting Insecticidal Hammocks to Prevent Forest Malaria in Vietnam
1 other identifier
interventional
18,646
1 country
1
Brief Summary
In Central Vietnam, forest malaria remains difficult to control due to the complex interactions between human, vector and environmental factors. Untreated bednets had a significantly protecting effect for villagers, except for those regularly sleeping in the forest, who suffer a significantly higher number of clinical attacks. Thus, there is need to target this high-risk group with new intervention based on long-lasting insecticidal materials. Hammocks are extensively used by people working in the forest, therefore long-lasting insecticidal hammocks (LLIH) could achieve a good individual protection. The Investigators proposed to evaluate their effectiveness in a community-based trial, comparing them to the standard vector control methods (insecticide-treated nets).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Mar 2004
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2004
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2006
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2007
CompletedFirst Submitted
Initial submission to the registry
February 27, 2009
CompletedFirst Posted
Study publicly available on registry
March 2, 2009
CompletedSeptember 14, 2010
September 1, 2010
2.8 years
February 27, 2009
September 12, 2010
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Reduction of malaria prevalence and incidence
24 months
Secondary Outcomes (1)
Reduction of malaria sero-prevalence
24 months
Study Arms (2)
Hammocks with LLIN
EXPERIMENTALLocally-made hammocks covered with long-lasting insecticidal net (LLIN)- Olyset(R), used in addition to the standard vector control measures
ITN
ACTIVE COMPARATORStandard vector control measures (insectice-treated net or ITN)
Interventions
Locally-made hammocks covered with long lasting insecticidal nel (LLIN)
Eligibility Criteria
You may qualify if:
- All residents in the 20 concerned study clusters and willing to give informed consent to participate
You may not qualify if:
- People not willing to give informed consent to participate
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ninh Thuan Provincial Malaria Station
Phan Rang-Tháp Chàm, Ninh Thuan, Vietnam
Related Publications (1)
Thang ND, Erhart A, Speybroeck N, Xa NX, Thanh NN, Ky PV, Hung le X, Thuan le K, Coosemans M, D'Alessandro U. Long-Lasting Insecticidal Hammocks for controlling forest malaria: a community-based trial in a rural area of central Vietnam. PLoS One. 2009 Oct 7;4(10):e7369. doi: 10.1371/journal.pone.0007369.
PMID: 19809502DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Annette Erhart, MD
Institute of Tropical Medicine
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
February 27, 2009
First Posted
March 2, 2009
Study Start
March 1, 2004
Primary Completion
December 1, 2006
Study Completion
June 1, 2007
Last Updated
September 14, 2010
Record last verified: 2010-09