Exercise Effects on Cardiovascular Risk Factors, Quality of Life, Muscle Function in Type 2 Diabetes and Healthy Persons
SMIDIG
Exercise - Effects on Health Related Quality of Life, Cardiovascular Risk Factors, and Cellular Functions With Respect to Glucose Metabolism, in Type 2 Diabetes Mellitus, Impaired Glucose Tolerance and in Healthy Individuals.
1 other identifier
interventional
213
1 country
1
Brief Summary
A sedentary lifestyle is known to be a risk factor to developing type 2 diabetes. The aim of this study was to determine the effects of adding regular Nordic walking to daily physical activity. Effects on quality of life, cardiovascular risk factors and functions in muscle cells will be determined.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable type-2-diabetes
Started Apr 2006
Typical duration for not_applicable type-2-diabetes
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2006
CompletedFirst Submitted
Initial submission to the registry
February 26, 2009
CompletedFirst Posted
Study publicly available on registry
February 27, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2009
CompletedMarch 2, 2009
February 1, 2009
3.4 years
February 26, 2009
February 27, 2009
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
HbA1c
at inclusion and after four months
Secondary Outcomes (1)
waist circumference
at inclusion and after four months
Study Arms (2)
Exercise
EXPERIMENTALFive hours of Nordic walking per week, during four months
Control
NO INTERVENTIONControl group asked not to alter lifestyle during study
Interventions
Nordic walking, with walking poles, five hours per week during four months
Eligibility Criteria
You may qualify if:
- BMI\>25
You may not qualify if:
- Physical impairment
- Symptomatic angina pectoris
- Insulin treatment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Primary health care center
Stockholm, SE 134 40, Sweden
Related Publications (2)
Osler ME, Fritz T, Caidahl K, Krook A, Zierath JR, Wallberg-Henriksson H. Changes in gene expression in responders and nonresponders to a low-intensity walking intervention. Diabetes Care. 2015 Jun;38(6):1154-60. doi: 10.2337/dc14-2606. Epub 2015 Mar 20.
PMID: 25795414DERIVEDFritz T, Caidahl K, Osler M, Ostenson CG, Zierath JR, Wandell P. Effects of Nordic walking on health-related quality of life in overweight individuals with type 2 diabetes mellitus, impaired or normal glucose tolerance. Diabet Med. 2011 Nov;28(11):1362-72. doi: 10.1111/j.1464-5491.2011.03348.x.
PMID: 21658122DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Juleen Zierath, Professor
Dep. of molecular medicine and surgery, Karolinska Institutet
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
February 26, 2009
First Posted
February 27, 2009
Study Start
April 1, 2006
Primary Completion
September 1, 2009
Study Completion
September 1, 2009
Last Updated
March 2, 2009
Record last verified: 2009-02