Comparison of Anwar and Melles Techniques in Deep Anterior Lamellar Keratoplasty (DALK) for Keratoconus Patients
1 other identifier
interventional
N/A
1 country
2
Brief Summary
This study will be performed on patients who come to labbafinejad ophthalmic clinic from 20 March 2008. Keratoconus diagnosis will be determined by clinical finding in slit lamp, keratometery and topographic characteristics. Patients will be randomly placed in group A and B. In group A, Anwar surgical method and in B, Melles surgical method, will be done. This is not a blind study due to surgeons' knowledge. All patients will receive Btamethazone drop and Chloramphenicol every 6 hours and will be tapered in two months. In the end anatomical results, complications, BCVA, UCVA, astigmatism, endothelial cell numbers will be compared in two groups by using specular microscopy. Contrast sensivity, central corneal diameter, interface wrinkling and opacity will be measured by metrovison, Confoscan, Photoslit in months 3, 6, 12, respectively and will be evaluated afterwards.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started May 2008
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2008
CompletedFirst Submitted
Initial submission to the registry
February 23, 2009
CompletedFirst Posted
Study publicly available on registry
February 24, 2009
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
September 1, 2009
CompletedJanuary 5, 2012
February 1, 2009
1.1 years
February 23, 2009
January 4, 2012
Conditions
Keywords
Study Arms (2)
Melles
EXPERIMENTALAnwar
EXPERIMENTALInterventions
Eligibility Criteria
You may qualify if:
- patients with keratoconus
- \<age\<45
- contact lens intolerance
You may not qualify if:
- Having a history of any other ophthalmic or systemic problem
- Central corneal scar
- descemet's membrane detachment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Ophtalmic Research Centre
Tehran, Tehran Province, 1666663111, Iran
Farid Karimian,MD
Tehran, Tehran Province, 166666, Iran
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
February 23, 2009
First Posted
February 24, 2009
Study Start
May 1, 2008
Primary Completion
June 1, 2009
Study Completion
September 1, 2009
Last Updated
January 5, 2012
Record last verified: 2009-02