NCT00848315

Brief Summary

The overall goal of this randomized clinical trial (RCT) is to test the efficacy of a culturally- and literacy-tailored cognitive-behavioral intervention designed to enhance adherence to diabetes self-management behaviors and improve glycemic control among low-income Hispanic individuals with type 2 diabetes mellitus.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
252

participants targeted

Target at P75+ for phase_2 type-2-diabetes

Timeline
Completed

Started Jul 2004

Longer than P75 for phase_2 type-2-diabetes

Geographic Reach
1 country

5 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2004

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2008

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

February 19, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 20, 2009

Completed
Last Updated

September 13, 2023

Status Verified

September 1, 2023

Enrollment Period

3.9 years

First QC Date

February 19, 2009

Last Update Submit

September 11, 2023

Conditions

Keywords

cognitive behavioral interventionlow literate/illiterate Hispanic patients

Outcome Measures

Primary Outcomes (1)

  • The primary outcome is improvement in metabolic control (HbA1c).

    The primary outcome was evaluated at 4- and 12-months following randomization.

Secondary Outcomes (1)

  • Efficacy of the intervention

    4- and 12-months following the intervention

Study Arms (2)

1

NO INTERVENTION

Usual Care that the Type 2 Diabetes Patients usually receive at the health centers.

2

EXPERIMENTAL

Cognitive Behavioral Intervention

Behavioral: Cognitive Behavioral Intervention

Interventions

The intervention emphasizes patients' ethnic preferences and traditions (e.g., adapting ethnic recipes to meet dietary goals) and the use of available community resources (e.g., available areas for exercise), and is delivered utilizing strategies and materials appropriate for low-literate/illiterate patients.

Also known as: Diabetes Self-Management
2

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosed with T2DM (documented in the medical chart);
  • HbA1c level \> 7.5;
  • Currently treated with diet, oral hypoglycemics or insulin. If currently on insulin, must have a history of prior therapy with diet alone or oral hypoglycemic agents;
  • Hispanic origin;
  • \> 18 years old;
  • Telephone in home or easy access to one;
  • Able to understand and participate in the study protocol;
  • Functionally capable of meeting the activity goals;
  • Understands and can provide informed consent (English or Spanish; for illiterate pts we will require that a representative of the pt also understands and signs the consent form on behalf of the pt);
  • Physician approval to participate in the study.

You may not qualify if:

  • History of diabetic ketoacidosis
  • Gestational diabetes
  • Unable or unwilling to provide informed consent;
  • Plans to move out of the area within the 12-month study period;
  • Required intermittent glucocorticoid therapy within the past 3 months;
  • Experienced an acute coronary event (myocardial infarction or unstable angina) within the previous 6 mos
  • Has a medical condition that precludes adherence to study dietary recommendations (e.g., Crohn's disease, ulcerative colitis, end-stage renal disease);
  • Has a medical or psychiatric illness (i.e., dementia, psychiatric hospitalization or suicidality within past 5 years or takes an atypical neuroleptic medication). We will not exclude individuals with a diagnosis of depression or pts taking anti-depressants.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (5)

Northgate Medical Center

Springfield, Massachusetts, 01103, United States

Location

Brightwood Health Center

Springfield, Massachusetts, 01107, United States

Location

High Street Health Center

Springfield, Massachusetts, 01199, United States

Location

Plumley Village

Worcester, Massachusetts, 01608, United States

Location

Family Health Center

Worcester, Massachusetts, 01610, United States

Location

Related Publications (2)

  • Wang ML, Gellar L, Nathanson BH, Pbert L, Ma Y, Ockene I, Rosal MC. Decrease in Glycemic Index Associated with Improved Glycemic Control among Latinos with Type 2 Diabetes. J Acad Nutr Diet. 2015 Jun;115(6):898-906. doi: 10.1016/j.jand.2014.10.012. Epub 2014 Dec 26.

  • Rosal MC, White MJ, Restrepo A, Olendzki B, Scavron J, Sinagra E, Ockene IS, Thompson M, Lemon SC, Candib LM, Reed G. Design and methods for a randomized clinical trial of a diabetes self-management intervention for low-income Latinos: Latinos en Control. BMC Med Res Methodol. 2009 Dec 9;9:81. doi: 10.1186/1471-2288-9-81.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Milagros C Rosal, PhD

    University of Massachusetts, Worcester

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 19, 2009

First Posted

February 20, 2009

Study Start

July 1, 2004

Primary Completion

June 1, 2008

Study Completion

July 1, 2008

Last Updated

September 13, 2023

Record last verified: 2023-09

Locations