Pathogen Identification of Bacterial Pneumonia Via DNA Detection
Identification of Bacterial Species and Their Antibiotic-Resistant Spectrum in Sputum Specimen From the Patients With Pneumonia Via Nuclear Acid Detection Assay
1 other identifier
observational
2,896
0 countries
N/A
Brief Summary
Pneumonia is a common cause of morbidity and mortality. The diagnosis of pneumonia from the microbiology perspective has been challenging. Recent reports suggest the utility of nuclear acid detection for rapid and accurate diagnoses of these pathogens and their antibiotic-resistant spectrum. Extracted bacterial nucleic acid in sputum specimen will be identified by Nuclear acid detection assay kit with Microfluidic Pumping Chip and LAMP methods
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2007
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2007
CompletedFirst Submitted
Initial submission to the registry
December 4, 2007
CompletedFirst Posted
Study publicly available on registry
December 5, 2007
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2009
CompletedJune 24, 2010
June 1, 2010
1.5 years
December 4, 2007
June 23, 2010
Conditions
Keywords
Eligibility Criteria
Greater than 18 years of age. Cough present greater than one day and a history of fever and X-ray evidence of pneumonia.
You may qualify if:
- Greater than 18 years of age.
- Cough present greater than one day
- History of fever
- X-ray evidence of pneumonia.
You may not qualify if:
- Pneumonia caused by TB, fungi and virus
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Kang Y, Deng R, Wang C, Deng T, Peng P, Cheng X, Wang G, Qian M, Gao H, Han B, Chen Y, Hu Y, Geng R, Hu C, Zhang W, Yang J, Wan H, Yu Q, Wei L, Li J, Tian G, Wang Q, Hu K, Wang S, Wang R, Du J, He B, Ma J, Zhong X, Mu L, Cai S, Zhu X, Xing W, Yu J, Deng M, Gao Z. Etiologic diagnosis of lower respiratory tract bacterial infections using sputum samples and quantitative loop-mediated isothermal amplification. PLoS One. 2012;7(6):e38743. doi: 10.1371/journal.pone.0038743. Epub 2012 Jun 14.
PMID: 22719933DERIVED
Biospecimen
DNA extracted from sputum specimen
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Zhancheng Gao, Professor
Peking University People's Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
December 4, 2007
First Posted
December 5, 2007
Study Start
December 1, 2007
Primary Completion
June 1, 2009
Study Completion
December 1, 2009
Last Updated
June 24, 2010
Record last verified: 2010-06