Investigating the Role of the Premotor Cortex in Higher Cognitive Functions

NCT00842413 | Terminated

• 1 other identifier: P060605
• Study Type: observational
• Target: 9
• Locations: 1 country
• Sites: 1

Brief Summary

This project aims at understanding better the role of the frontal lobe of the brain in our capacity to perceive visual information consciously, and also, in our capacity to perceive others' actions. It includes a test where we ask subjects to detect visual information in front of a computer screen, and another test where we ask them to imitate finger movements.

Conditions

Brain Injury; Chronic

Keywords

Prefrontal cortex; visual consciousness; focal lesions; action perception

Study Arms (2)

1

The study compares brain-damaged patients with healthy ones on two psychophysical tasks.

2

The study does not intervene on the brain-damaged patients, it merely compares their behaviour with that of healthy patients on a range of psychophysical tasks.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The visual pereption of subjects willl be studied, but no attempt will be made at modifying it, or treating any problem that they might have.

You may qualify if:

• Healthy subjects chosen from a pool of adult subjects, recruited through ads.
• In the second group, the subjects are recruited from a pool of brain-damaged patients treated at the hospital de la Pitié-Salpétrière. They must suffer from a focal lesion in the prefrontal cortex.

You may not qualify if:

• For the healthy group: any previous brain-related medical history.
• Widespread brain-damage, extending beyond the prefrontal cortex, that is to say, lesions that are not really focal.

Sponsors & Collaborators

• Assistance Publique - Hôpitaux de Paris: lead

Study Sites (1)

Hôpital de la Pitié-Salpétrière

Paris, 75013, France

Location

MeSH Terms

Conditions

Brain Injuries; Bronchiolitis Obliterans Syndrome

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Craniocerebral Trauma; Trauma, Nervous System; Wounds and Injuries; Organizing Pneumonia; Bronchiolitis Obliterans; Bronchiolitis; Bronchitis; Bronchial Diseases; Respiratory Tract Diseases; Lung Diseases, Obstructive; Lung Diseases; Graft vs Host Disease; Immune System Diseases

Study Officials

• Richard Levy, MD

  Assistance Publique - Hôpitaux de Paris

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: February 11, 2009
• First Posted: February 12, 2009
• Study Start: May 1, 2007
• Primary Completion: September 1, 2007
• Study Completion: September 1, 2007
• Last Updated: February 12, 2009

Record last verified: 2008-11

Locations

FR (1)