NCT00841685

Brief Summary

Implantation of fiducial markers in the prostate and daily check of the positioning during radiotherapy based on the implanted fiducial markers

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable prostate-cancer

Timeline
Completed

Started Dec 2008

Typical duration for not_applicable prostate-cancer

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2008

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 10, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 11, 2009

Completed
3.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2012

Completed
Last Updated

January 5, 2023

Status Verified

January 1, 2023

Enrollment Period

3.4 years

First QC Date

February 10, 2009

Last Update Submit

January 3, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Acute toxicity after implantation of the fiducial gold markers

    1 week after implantation

Secondary Outcomes (2)

  • Feasibility of insertion 1 fiducial gold marker in the intraprostatic lesion combined with extra gold markers in the rest of the prostate upto 3 goldmarkers in total

    1 week after implantation

  • Visualization of the implanted gold markers by ultrasound

    After implantation

Study Arms (5)

1

EXPERIMENTAL

Goldlock

Device: Goldlock

2

ACTIVE COMPARATOR

Visicoil smallest size

Device: Visicoil smallest size

3

ACTIVE COMPARATOR

Visicoil larger size

Device: Visicoil larger size

4

ACTIVE COMPARATOR

Bard goldmarker smallest size

Device: Bard goldmarker smallest size

5

ACTIVE COMPARATOR

Bard goldmarker larger size

Device: Bard goldmarker larger size

Interventions

GoldlockDEVICE

Insertion of Goldlock marker

1

Insertion of Visicoil, smallest size, marker

2

Insertion of Visicoil, larger size, marker

3

Insertion of Bard goldmarker, smallest size

4

Insertion of Bard goldmarker, larger size

5

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • histological proven adenocarcinoma of the prostate
  • T1-T4 tumors
  • Radiotherapy as primary therapy +/- androgen deprivation
  • Presence of an intraprostatic lesion (IPL) on MRI/MRS
  • Presence of an intraprostatic lesion (IPL) on ultrasound
  • WHO 0-2

You may not qualify if:

  • Other primary tumor, except non-melanoma skin cancer
  • No written informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Ghent

Ghent, 9000, Belgium

Location

Related Links

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

  • Gert De Meerleer, MD, PhD

    University Hospital, Ghent

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 10, 2009

First Posted

February 11, 2009

Study Start

December 1, 2008

Primary Completion

May 1, 2012

Study Completion

May 1, 2012

Last Updated

January 5, 2023

Record last verified: 2023-01

Locations