NCT00836121

Brief Summary

The investigators report a case of a 39-year-old man who presented an anterior mediastinal cystic mature teratoma. Those kind of tumor contain elements derived from more than one of the three primary germ layers (ectoderm, mesoderm, endoderm), frequently arranged in a haphazard manner. They arise from totipotent cells and, therefore, are primarily found in gonads, and more rarely in primitive cells kidnapped in other parts of the body. The tissues are immature to well differentiated and foreign to the anatomic site. Mature teratomas are either cystic or solid, although the cystic presentation predominates in gonadal sites. Benign teratomas are the most common mediastinal germ cell tumor, accounting 70% of the mediastinal germ cell tumors in children and 60% of those in adults. Immature teratomas are potentially malignant tumors; their prognosis is influenced by the anatomic site of the tumor, patient age, and the fraction of the tumor that is immature. Treatment of benign mediastinal teratoma includes complete surgical resection, with results in a excellent long-term cure rates. Complete resection of teratomas should be the goal of treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Sep 2008

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2008

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2008

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 2, 2009

Completed
2 days until next milestone

First Posted

Study publicly available on registry

February 4, 2009

Completed
Last Updated

February 4, 2009

Status Verified

February 1, 2009

Enrollment Period

2 months

First QC Date

February 2, 2009

Last Update Submit

February 3, 2009

Conditions

Teratoma

Keywords

TeratomaMediastinum

Outcome Measures

Primary Outcomes (1)

  • cure

    one month after surgery

Study Arms (1)

tumor

Procedure: right thoracotomy

Interventions

right thoracotomyPROCEDURE

complete surgical resection

tumor

Eligibility Criteria

Age39 Years - 39 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

primary care clinic

You may qualify if:

  • Clinical diagnosis of mediastinum teratoma

You may not qualify if:

  • Tumor absent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculdade de medicina de Catanduva

Catanduva, São Paulo, 15809-145, Brazil

Location

MeSH Terms

Conditions

Teratoma

Condition Hierarchy (Ancestors)

Neoplasms, Germ Cell and EmbryonalNeoplasms by Histologic TypeNeoplasms

Study Officials

  • Stella MF Giolo, student

    Faculdade de Medicina de Catanduva

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Sponsor Type
OTHER

Study Record Dates

First Submitted

February 2, 2009

First Posted

February 4, 2009

Study Start

September 1, 2008

Primary Completion

November 1, 2008

Study Completion

December 1, 2008

Last Updated

February 4, 2009

Record last verified: 2009-02

Locations

BR(1)