NCT00835133

Brief Summary

RATIONALE: Collecting and storing samples of blood and tissue from family members of patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This clinical trial is collecting blood and tissue samples from family members of patients with pancreatic disease, pancreatic cancer, and melanoma.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,122

participants targeted

Target at P75+ for all trials

Timeline
17mo left

Started Aug 2002

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress94%
Aug 2002Sep 2027

Study Start

First participant enrolled

August 1, 2002

Completed
6.5 years until next milestone

First Submitted

Initial submission to the registry

January 31, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 3, 2009

Completed
18.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2027

Last Updated

March 6, 2026

Status Verified

March 1, 2026

Enrollment Period

25.2 years

First QC Date

January 31, 2009

Last Update Submit

March 5, 2026

Conditions

Familial Pancreatic Cancer

Keywords

familyhistorypancreascancermelanomagenetic

Outcome Measures

Primary Outcomes (1)

  • Collection of familial data and biospecimens in a data and tissue repository for familial pancreas research

    baseline

Interventions

medical chart reviewOTHER

confirmation of cancer diagnosis

survey administrationOTHER

at baseline enrollment and 12 months post-enrollment

biologic sample preservation procedureOTHER

one blood sample

Eligibility Criteria

Age18 Years - 120 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Familial pancreatic cancer kindred

DISEASE CHARACTERISTICS: * Meets 1 of the following criteria: * Has at least 2 blood relatives with pancreatic cancer (both must be related) * Has at least 1 blood relative with pancreatic cancer and 1 with melanoma (both must be related) PATIENT CHARACTERISTICS: * Mentally competent and able to provide informed consent * Able to understand and read English PRIOR CONCURRENT THERAPY: * Not specified

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Study Sites (1)

Mayo Clinic Cancer Center

Rochester, Minnesota, 55905, United States

Location

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

Two 10mL plasma tubes and two 10mL serum tubes collected. DNA extracted from blood lymphocytes.

MeSH Terms

Conditions

Pancreatic carcinoma, familialNeoplasmsMelanoma

Condition Hierarchy (Ancestors)

Neuroendocrine TumorsNeuroectodermal TumorsNeoplasms, Germ Cell and EmbryonalNeoplasms by Histologic TypeNeoplasms, Nerve TissueNevi and MelanomasSkin NeoplasmsNeoplasms by SiteSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Shounak Majumder, M.D.

    Mayo Clinic

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
FAMILY BASED
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

January 31, 2009

First Posted

February 3, 2009

Study Start

August 1, 2002

Primary Completion (Estimated)

September 30, 2027

Study Completion (Estimated)

September 30, 2027

Last Updated

March 6, 2026

Record last verified: 2026-03

Locations

US(1)