Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants

NCT00992303 | Recruiting DMC

• 3 other identifiers: STU 072010-098SCCC-032009-049CDR0000653406
• Study Type: observational
• Target: 10,000
• Locations: 1 country
• Sites: 1

Brief Summary

RATIONALE: Collecting and storing samples of tissue from patients with cancer to test in the laboratory may help the study of cancer in the future. PURPOSE: This research study is collecting tissue samples from patients with cancer undergoing radiation therapy. Healthy participants will also be allowed on the trial so their samples can be used in comparison to patients with malignancy

Conditions

Unspecified Adult Solid Tumor, Protocol Specific

Keywords

unspecified adult solid tumor, protocol specific

Outcome Measures

Primary Outcomes (1)

• Maintenance a Tissue Resource and Registry/Database

  Maintenance and creation of a University of Texas Southwestern Medical Center (UTSW) Radiation Oncology Tissue Resource and Registry/Database

  10 years

Secondary Outcomes (5)

• Local recurrence

  5 years

• Distant metastasis

  5 years

• Overall survival

  5 years

• Toxicity by treatment regimen

  1 year

• Establishment of a prospective registry/database

  10 years

Interventions

biologic sample preservation procedure OTHER

medical chart review OTHER

questionnaire administration OTHER

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Cancer patients, healthy volunteers

DISEASE CHARACTERISTICS: * Pathologically-proven diagnosis of malignancy * Planning treatment with radiation therapy PATIENT CHARACTERISTICS: * Able to perform follow-up visits * Is a patient of the University of Texas Southwestern Medical Center physicians PRIOR CONCURRENT THERAPY: * See Disease Characteristics * Participation in other clinical trials is allowed * Other prior or concurrent therapy for cancer, such as surgery and/or chemotherapy, is allowed. Criteria for eligibility: * Able to provide written informed consent * Age greater than 18 years old * Males and Females are eligible * Any ethnicity is eligible Criteria for ineligibility: -Patients not available for follow-up/future contact

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• University of Texas Southwestern Medical Center: lead

Study Sites (1)

UT Southwestern Medical Center

Dallas, Texas, 75390, United States

RECRUITING

Study Officials

• Robert Timmerman, MD

  University of Texas Southwestern Medical Center - Dallas

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Suprabha Pulipparacharuvil

CONTACT

214-645-8525; suprabha.pulipparacharuvil@utsouthwestern.edu

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: October 8, 2009
• First Posted: October 9, 2009
• Study Start: September 1, 2009
• Primary Completion (Estimated): December 1, 2029
• Study Completion (Estimated): December 1, 2029
• Last Updated: May 14, 2025

Record last verified: 2025-05

Locations

US (1)