NCT00834015

Brief Summary

The aim of the present study is to analyse the significance of postoperative combined strength and aerobic training for outcome of the lumbar fusion patients compared to usual care (patients with isthmic or degenerative spondylolisthesis).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2010

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 30, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 2, 2009

Completed
1.2 years until next milestone

Study Start

First participant enrolled

May 1, 2010

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

April 14, 2015

Status Verified

April 1, 2015

Enrollment Period

2.6 years

First QC Date

January 30, 2009

Last Update Submit

April 13, 2015

Conditions

Keywords

spinal fusionpaindisabilitymuscle strengthmobilityquality of lifelumbaristhmic or degenerative spondylolisthesis

Outcome Measures

Primary Outcomes (3)

  • pain

    visual analogue scale (VAS)

    baseline, 1 year (+ 1 year follow-up)

  • disability

    baseline, 1 year (+ 1 year follow-up)

  • quality of life

    baseline, 1 year (+ 1 year follow-up)

Secondary Outcomes (5)

  • trunk muscle strength

    baseline, 1 year

  • spine mobility

    baseline, 1 year

  • fear of movement

    baseline, 1 year postoperatively

  • physical activity

    baseline, 1 year

  • depressive symptoms

    baseline, 1 year

Study Arms (1)

Experimental

OTHER

combined strength and aerobic training

Other: Outcome of lumbar spinal fusion patients and significance of postoperative exercise therapy: A randomized controlled trial

Interventions

combined strength and aerobic training group

Also known as: Intervention group
Experimental

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • over 20 years old
  • isthmic or degenerative spondylolisthesis

You may not qualify if:

  • cardiovascular or musculoskeletal diseases, which may exclude their ability to perform strength and endurance training and testing
  • metabolic bone disease
  • psychosocial instability
  • malignant disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Jyväskylä Central Hospital

Jyväskylä, 40620, Finland

Location

Related Publications (1)

  • Tarnanen S, Neva MH, Dekker J, Hakkinen K, Vihtonen K, Pekkanen L, Hakkinen A. Randomized controlled trial of postoperative exercise rehabilitation program after lumbar spine fusion: study protocol. BMC Musculoskelet Disord. 2012 Jul 20;13:123. doi: 10.1186/1471-2474-13-123.

MeSH Terms

Conditions

SpondylolisthesisPain

Condition Hierarchy (Ancestors)

SpondylolysisSpondylosisSpinal DiseasesBone DiseasesMusculoskeletal DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Arja Häkkinen, Professor

    Department of Health Sciences, University of Jyväskylä

    STUDY DIRECTOR
  • Marko Neva, Phd, MD

    Tampere University Hospital

    PRINCIPAL INVESTIGATOR
  • Keijo Häkkinen, professor

    Department of Biology of Physical Activity, University of Jyväskylä

    PRINCIPAL INVESTIGATOR
  • Joost Dekker, professor

    Department of Rehabilitation Medicine, VU University Medical Center, Amsterdam, the Netherlands

    PRINCIPAL INVESTIGATOR
  • Kimmo Vihtonen, Phd, MD

    Department of Surgery, University of Tampere

    PRINCIPAL INVESTIGATOR
  • Outi Ilves, Msc, PT

    Department of Health Sciences University of Jyvaskyla

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

January 30, 2009

First Posted

February 2, 2009

Study Start

May 1, 2010

Primary Completion

December 1, 2012

Study Completion

December 1, 2012

Last Updated

April 14, 2015

Record last verified: 2015-04

Locations