NCT00833092

Brief Summary

Insomnia is not a natural part of aging but is higher in older adults because of a variety of factors common in later life. One of these factors may be a deficient magnesium status. This study will look at whether or not magnesium supplementation will improve sleep.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
111

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2008

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2008

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2008

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 27, 2009

Completed
3 days until next milestone

First Posted

Study publicly available on registry

January 30, 2009

Completed
3.2 years until next milestone

Results Posted

Study results publicly available

April 4, 2012

Completed
Last Updated

March 26, 2015

Status Verified

March 1, 2015

Enrollment Period

11 months

First QC Date

January 27, 2009

Results QC Date

July 27, 2011

Last Update Submit

March 6, 2015

Conditions

Keywords

magnesiumNutritional RequirementsSleep

Outcome Measures

Primary Outcomes (1)

  • Global Pittsburgh Sleep Quality Index

    Improvement in the Pittsburgh Global Sleep Quality Index (PGQI). The index is based on a score of 0 to 21, the lower the score on the index the better the subject perceives their sleep.

    9 weeks

Study Arms (2)

Sugar pill

PLACEBO COMPARATOR

Sugar Pill

Dietary Supplement: Sugar Pill

magnesium

ACTIVE COMPARATOR

300 milligrams of magnesium daily

Dietary Supplement: magnesium

Interventions

Sugar PillDIETARY_SUPPLEMENT

Sugar pill supplementation for 9 weeks

Sugar pill
magnesiumDIETARY_SUPPLEMENT

300 milligrams daily for 8 weeks

magnesium

Eligibility Criteria

Age51 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • have sleep complaints
  • Score greater than 5 on Pittsburgh Global Sleep Quality Index

You may not qualify if:

  • taking medications that affect sleep
  • taking 100 milligrams or more of magnesium
  • body mass index of 40 or higher
  • abnormal breathing conditions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

USDA Grand Forks Human Nutrition Research Center

Grand Forks, North Dakota, 58202, United States

Location

Related Publications (3)

  • Foley DJ, Monjan AA, Brown SL, Simonsick EM, Wallace RB, Blazer DG. Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep. 1995 Jul;18(6):425-32. doi: 10.1093/sleep/18.6.425.

    PMID: 7481413BACKGROUND
  • Hunt CD, Johnson LK. Magnesium requirements: new estimations for men and women by cross-sectional statistical analyses of metabolic magnesium balance data. Am J Clin Nutr. 2006 Oct;84(4):843-52. doi: 10.1093/ajcn/84.4.843.

    PMID: 17023712BACKGROUND
  • Ford ES, Mokdad AH. Dietary magnesium intake in a national sample of US adults. J Nutr. 2003 Sep;133(9):2879-82. doi: 10.1093/jn/133.9.2879.

    PMID: 12949381BACKGROUND

MeSH Terms

Conditions

MalnutritionSleep Initiation and Maintenance Disorders

Interventions

SugarsMagnesium

Condition Hierarchy (Ancestors)

Nutrition DisordersNutritional and Metabolic DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Intervention Hierarchy (Ancestors)

CarbohydratesMetals, Alkaline EarthElementsInorganic ChemicalsMetals, LightMetals

Results Point of Contact

Title
Forrest H Nielsen, PhD
Organization
USDA Grand Forks Human Nutrition ResearchCenter

Study Officials

  • Forrest H Nielsen, PhD

    USDA Grand Forks Human Nutrition Research Center

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 27, 2009

First Posted

January 30, 2009

Study Start

January 1, 2008

Primary Completion

December 1, 2008

Study Completion

December 1, 2008

Last Updated

March 26, 2015

Results First Posted

April 4, 2012

Record last verified: 2015-03

Locations