Effects of Ritalin on Postural Stability of Old Adults

NCT00817960 | Completed DMC

• 2 other identifiers: SOR476508CTILMZ4765
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Experimental design overview The proposed project is a prospective experimental study design. independent old adults(age 65 years old and older) who do not suffer from balance problems willing to participate in the study will be tested with well-established measuring techniques of Balance control before and 2 hours after taking of Methylphenidate (Ritalin) in the movement and Rehabilitation Laboratory at BGU. An automated algorithm will be used to extract standardized stabilogram-diffusion parameters from each of the COP data sets collected during quiet standing. These parameters include diffusion coefficients, critical displacement, critical time and scaling exponents for both lateral and anterior-posterior sway directions (Collins \& De Luca, 1993). For each of the conditions (before and 1 hour after the use of Ritalin) in three task conditions single task; dual task (concentrating and identifying specific music); and just Listening to a relaxing music. Participants will be required to stand on the platform 10 times for 30 s. For each trial, they will be instructed to sway as little as possible.

Conditions

Postural Imbalance

Keywords

Dual tasking; Postural Control; Methylphenidate (Ritalin); old adults

Outcome Measures

Primary Outcomes (1)

• Postural sway measures

  Time 1: pre test' and hour later time 2: post testinng proceedure

Study Arms (1)

Methylphenidate

EXPERIMENTAL

Drug: Methylphenidate

Interventions

Methylphenidate DRUG

The effect of ritalin on postural stability of old adults (65 years old and over) will be measured using RCT study design

Methylphenidate

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Age 65 years old and older
• independent elderly adults
• do not suffer from balance prblems
• minimental score 24 and above

You may not qualify if:

• old adults who suffer from neurological disease or stroke
• old adults who suffer from psychiatric state
• old adults who suffer from orthopedic condition (1/2 a year after a fracture in the lower limb)
• old adults who suffer from heart conditions
• old adults who suffer from blindness

Sponsors & Collaborators

• Soroka University Medical Center: lead

Study Sites (1)

SorokaUMC

Beersheba, Israel, 84105, Israel

Location

MeSH Terms

Interventions

Methylphenidate

Intervention Hierarchy (Ancestors)

Phenylacetates; Acids, Carbocyclic; Carboxylic Acids; Organic Chemicals; Piperidines; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds

Study Officials

• Itshak Melzer, PhD

  Ben-gurion University of the Negev, Beer-Sheva, Israel

  PRINCIPAL INVESTIGATOR

• Zmir Shorer, m

  Soroka University Medical Centar

  STUDY CHAIR

• Yan Press, MD

  Soroka University Medical Center

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 6, 2009
• First Posted: January 7, 2009
• Study Start: July 1, 2011
• Primary Completion: January 1, 2012
• Study Completion: June 1, 2012
• Last Updated: June 20, 2012

Record last verified: 2008-12

Locations

IL (1)