NCT00817232

Brief Summary

Tennis elbow is a relatively common musculoskeletal disorder that can cause significant pain and disability. Treatment of the disorder is not always successful, and it often recurs or becomes chronic. More effective management options are required. There is evidence that electric microcurrent can promote tissue healing and symptom resolution in various chronic hard and soft tissue disorders, but few human studies investigating its use with chronic tendon problems. It is an easily applied therapy with very few reports of side effects. It can be applied at home using a portable unit and, if it is clinically effective, may also prove more cost effective than other therapies. A clinical trial is planned to evaluate the therapy but, in the absence of relevant published evidence, a preliminary study is required to look for a treatment effect and inform a power calculation for sample size, The study will also allow some investigation of dose-dependence, which is a key issue in many forms of electrotherapy. Finally it will enable evaluation of elements of the full trial protocol so that any weaknesses can be addressed before it begins.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for phase_2

Timeline
Completed

Started Dec 2008

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2008

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

January 5, 2009

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 6, 2009

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
Last Updated

June 22, 2010

Status Verified

August 1, 2009

Enrollment Period

1 year

First QC Date

January 5, 2009

Last Update Submit

June 18, 2010

Conditions

Keywords

tennis elbowmicrocurrenttissue healing

Outcome Measures

Primary Outcomes (2)

  • Tendon pathology as indicated by sonography

    baseline, 3 weeks, 6 weeks, 4 months

  • Patient-Rated Global Change Score

    3 weeks, 6 weeks, 4 months

Secondary Outcomes (4)

  • Pain Free Grip Strength

    baseline, 3 weeks, 6 weeks, 4 months

  • Patient-rated Tennis Elbow Questionnaire

    baseline, 3 weeks, 6 weeks, 4 months

  • Patient-Specific Functional Scale

    baseline, 3 weeks, 6 weeks, 4 months

  • Adverse events

    3 weeks, 6 weeks, 4 months

Study Arms (2)

Treatment 1

EXPERIMENTAL

50 microamp amplitude

Device: Microcurrent (Elexoma Medic)

Treatment 2

EXPERIMENTAL

500 microamp amplitude

Device: Microcurrent (Elexoma Medic)

Interventions

monophasic frequency modulated square wave current applied for 99 minutes daily for 21 days

Also known as: Elexoma Medic
Treatment 1Treatment 2

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • symptoms of tennis elbow for at least 3 months
  • clinical diagnosis of tennis elbow

You may not qualify if:

  • significant symptom improvement in previous month
  • receipt of any active treatment for the condition in the previous month
  • currently under the care of another health professional for tennis elbow
  • current cervical radiculopathy
  • other pathology affecting distal upper limb

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Hertfordshire

Hatfield, Hertfordshire, AL10 9AB, United Kingdom

Location

Related Links

MeSH Terms

Conditions

Tennis Elbow

Condition Hierarchy (Ancestors)

Elbow TendinopathyTendinopathyMuscular DiseasesMusculoskeletal DiseasesElbow InjuriesArm InjuriesWounds and InjuriesTendon Injuries

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 5, 2009

First Posted

January 6, 2009

Study Start

December 1, 2008

Primary Completion

December 1, 2009

Study Completion

December 1, 2009

Last Updated

June 22, 2010

Record last verified: 2009-08

Locations