NCT00809107

Brief Summary

The rational of the study is to assess the implantation, pregnancy and live birth rates after the transfer of frozen- thawed embryos in natural cycles with spontaneous Luteinizing Hormone (LH)/Progesterone rise or in natural cycles controlled by human chorionic gonadotropin (hCG) for final oocyte maturation and ovulation.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2006

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2006

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2008

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

December 16, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 17, 2008

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2009

Completed
Last Updated

February 19, 2009

Status Verified

February 1, 2009

Enrollment Period

1.8 years

First QC Date

December 16, 2008

Last Update Submit

February 18, 2009

Conditions

Infertility

Keywords

natural cycleFETspontaneous LH picHCG

Outcome Measures

Primary Outcomes (1)

  • Implantation rate

    2 years

Secondary Outcomes (1)

  • Ongoing pregnancy rate

    2 years

Study Arms (2)

1

EXPERIMENTAL

HCG GROUP

Drug: HCG

2

NO INTERVENTION

LH pick

Interventions

HCGDRUG

5000IU

Also known as: pregnyl
1

Eligibility Criteria

Age17 Years - 40 Years
Sexfemale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • age \<40
  • BMI:18-29Kg/m2
  • day 3 embryo transfers
  • previously IVF or ICSI

You may not qualify if:

  • irregular cycles
  • oocyte donation cycles

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre of Reproductive Medicine

Brussels, 1090, Belgium

Location

Related Publications (1)

  • Gelbaya TA, Nardo LG, Hunter HR, Fitzgerald CT, Horne G, Pease EE, Brison DR, Lieberman BA. Cryopreserved-thawed embryo transfer in natural or down-regulated hormonally controlled cycles: a retrospective study. Fertil Steril. 2006 Mar;85(3):603-9. doi: 10.1016/j.fertnstert.2005.09.015.

    PMID: 16500326BACKGROUND

MeSH Terms

Conditions

Infertility

Interventions

Chorionic Gonadotropin

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Intervention Hierarchy (Ancestors)

GonadotropinsPeptide HormonesHormonesHormones, Hormone Substitutes, and Hormone AntagonistsPlacental HormonesPeptidesAmino Acids, Peptides, and ProteinsPregnancy ProteinsProteins

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 16, 2008

First Posted

December 17, 2008

Study Start

October 1, 2006

Primary Completion

July 1, 2008

Study Completion

January 1, 2009

Last Updated

February 19, 2009

Record last verified: 2009-02

Locations

BE(1)