NCT00800371

Brief Summary

Juvenile idiopathic arthritis (JIA) may progress asymptomatically leading to joint destruction despite treatment. The aim of the observational study is to describe patients with silent arthritis comparing symptoms, clinical findings with results of ultrasound and magnetic resonance imaging (MRI).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started May 2008

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2008

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

December 1, 2008

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 2, 2008

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2009

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2010

Completed
Last Updated

December 2, 2008

Status Verified

November 1, 2008

Enrollment Period

1.6 years

First QC Date

December 1, 2008

Last Update Submit

December 1, 2008

Conditions

Juvenile Idiopathic Arthritis

Keywords

JIA

Outcome Measures

Primary Outcomes (1)

  • Definition of patients with silent arthritis.

    every three to six months from recruitment to end of study

Secondary Outcomes (1)

  • Comparison of diagnostic value of MRI and ultrasound.

    every three to six months from recruitment to end of study

Study Arms (1)

JIA

Patients with JIA

Procedure: intra-articular steroid injection

Interventions

intra-articular steroid injectionPROCEDURE

Steroid injection into otherwise noncontrollable arthritis.

JIA

Eligibility Criteria

Age7 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Patients with JIA

You may qualify if:

  • children without symptoms or with only mild joints swelling or with only minimal limited range of motion

You may not qualify if:

  • patients with manifest arthritis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Children's Hospital

Tübingen, Baden-Wurttemberg, 72076, Germany

RECRUITING

MeSH Terms

Conditions

Arthritis, Juvenile

Interventions

Steroids

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

Fused-Ring CompoundsPolycyclic Compounds

Study Officials

  • Nikolay Tzaribachev, MD

    University Hospital Tuebingen

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Nikolay Tzaribachev, MD

CONTACT

+49707129nikolay.tzaribachev@med.uni-tuebingen.de

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

December 1, 2008

First Posted

December 2, 2008

Study Start

May 1, 2008

Primary Completion

December 1, 2009

Study Completion

June 1, 2010

Last Updated

December 2, 2008

Record last verified: 2008-11

Locations

DE(1)