NCT00800163

Brief Summary

The investigators prospectively determined the impact on median door-to-balloon time of a protocol mandating (1) emergency department physician activation of the catheterization lab and (2) immediate transfer of the patient to an immediately available catheterization lab by an in-house transfer team consisting of an emergency department nurse, a critical care unit nurse, and a chest pain unit nurse.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2005

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2005

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

November 26, 2008

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 1, 2008

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2012

Completed
Last Updated

July 23, 2010

Status Verified

November 1, 2008

Enrollment Period

7 years

First QC Date

November 26, 2008

Last Update Submit

July 22, 2010

Conditions

Outcome Measures

Primary Outcomes (1)

  • Door-to-Balloon Time

    24 hours

Secondary Outcomes (4)

  • Infarct Size

    48 hours

  • In-Hospital Mortality

    ~ 7 days (during index hospitalization)

  • Hospital Length of Stay

    ~2-7 days (during index hospitalization)

  • Hospital Costs

    ~2-7 days (during Index Hospitalization) and One Year Followup

Study Arms (1)

ED Physician Activation/Immediate Transfer

EXPERIMENTAL
Other: ED Activation/Immediate Transfer

Interventions

ED Physician Activation and Immediate Transfer Protocol - see Circulation. 2007;116:67-76

ED Physician Activation/Immediate Transfer

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • ST-elevation myocardial infarction patients who undergo percutaneous intervention within 24 hours of ED arrival

You may not qualify if:

  • Patients who are inpatients
  • A registry of all patients who undergo emergency cardiac catheterization irrespective of etiology is maintained.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

St. Francis Heart Center

Indianapolis, Indiana, 46259, United States

RECRUITING

Related Publications (2)

  • Khot UN, Johnson ML, Ramsey C, Khot MB, Todd R, Shaikh SR, Berg WJ. Emergency department physician activation of the catheterization laboratory and immediate transfer to an immediately available catheterization laboratory reduce door-to-balloon time in ST-elevation myocardial infarction. Circulation. 2007 Jul 3;116(1):67-76. doi: 10.1161/CIRCULATIONAHA.106.677401. Epub 2007 Jun 11.

  • Khot UN, Johnson-Wood ML, Geddes JB, Ramsey C, Khot MB, Taillon H, Todd R, Shaikh SR, Berg WJ. Financial impact of reducing door-to-balloon time in ST-elevation myocardial infarction: a single hospital experience. BMC Cardiovasc Disord. 2009 Jul 26;9:32. doi: 10.1186/1471-2261-9-32.

MeSH Terms

Conditions

Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Umesh N Khot, M.D.

    Indiana Heart Physicians/St. Francis Heart Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Umesh N Khot, M.D.

CONTACT

Michele Johnson-Wood, R.N

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

November 26, 2008

First Posted

December 1, 2008

Study Start

September 1, 2005

Primary Completion

September 1, 2012

Study Completion

September 1, 2012

Last Updated

July 23, 2010

Record last verified: 2008-11

Locations