NCT00785811

TerminatedPhase 4

Effect of Chronic Supplementation of L-arginine in the Muscu...

Sanofi Source

Sanofi

ClinicalTrials.gov

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Other study identifiers

Sponsor study identifier

LARAS_L_02921

Study Type

interventional

Actual enrollment (reported)

36

Locations

1 country

Sites

1

Timeline

Study Start

October 2008

Date type not reported

This date has not been verified as actual or estimated.

Primary Completion

December 2008

Actual (reported)

Study Completion

December 2008

Actual (reported)

Brief Summary

The primary purpose of this study is to evaluate the effect of oral administration of L-arginine in the muscular fatigue of the quadriceps, expressed in terms of the Fatigue Resistance Factor (FRF). The secondary purpose of this study is to evaluate the effect of oral administration of L-arginine in the muscular force the quadriceps.

Registry Overview

Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.

Recruitment status: terminated
Actual enrollment (reported): 36 participants
Study completion date: December 2008
Actual (reported)
Listed locations: 1 countries · 1 sites

Trial Relationships

Click on a node to explore related trials.

Some registry-reported names shown below are not yet linked in this graph.

Study Timeline

Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.

Study Start
October 2008
Date type not reported
This date has not been verified as actual or estimated.
First Submitted
November 4, 2008
Actual (reported)
First Posted
November 5, 2008
Actual (reported)
Primary Completion
December 2008
Actual (reported)
Study Completion
December 2008
Actual (reported)

Last Updated: March 16, 2011
Status Verified: March 2011
Last Update Submitted: March 15, 2011

Conditions

Muscular Fatigue

Outcome Measures

Primary Outcomes (1)

Fatigue Resistance Factor (FRF)
Throughout the study

Secondary Outcomes (3)

Maximum force in Newton (N) and fast or explosive force
at time 30% of the maximum isometric force
Maximum force in Newton (N) and fast or explosive force
at time 50% of the maximum isometric force
Maximum force in Newton (N) and fast or explosive force
at time 90% of the maximum isometric force

Study Arms (2)

1

EXPERIMENTAL

L-arginine aspartate (Targifor)

Drug: L-arginine aspartate (Targifor)

2

PLACEBO COMPARATOR

Placebo

Drug: Placebo L-arginine aspartate (Targifor)

Interventions

L-arginine aspartate (Targifor)Drug

3g of L-arginine taken orally in a single daily dose for 8 weeks

1

Placebo L-arginine aspartate (Targifor)Drug

Placebo of L-arginine taken orally in a single daily dose for 8 weeks

2

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age20 Years - 55 Years

Sexall

Healthy VolunteersYes

Age GroupsAdult (18-64)

You may qualify if:

Healthy young adults for both sex; Age between 20 and 55 years; Slight or moderate physical activity, 30 minutes per day, at least 3 times a week;

You may not qualify if:

Sponsors & Collaborators

Sanofi
Industrylead

Study Sites (1)

Sanofi-Aventis Administrative Office

São Paulo, Brazil

Study Officials

Jaderson Lima
Sanofi
STUDY DIRECTOR

Enrollment

36 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: phase 4
Allocation: RANDOMIZED
Masking: DOUBLE
Who Masked: PARTICIPANT, INVESTIGATOR
Purpose: SUPPORTIVE CARE
Intervention Model: PARALLEL
Sponsor Type: INDUSTRY

Study Record Dates

First Submitted

November 4, 2008

First Posted

November 5, 2008

Study Start

October 2008

Date type not reported

This date has not been verified as actual or estimated.

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The Effect of Transcutaneous Electrical Nerve Stimulation on People With Muscle Fatigue Due to Training, Sports

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NCT04415099

Tibialis Posterior Fatigue and Plantar Pressure

Not ApplicableCompleted

NCT03998280

The Effect Of Cervical Muscle Fatigue in Neck Proprioception and Postural Stability

Unknown

NCT04367727

Effect of Light Emitting Diode Therapy on Muscle Fatigue

Not ApplicableUnknown

NCT07665008

MULTİDİMENSİONAL ASSESSMENT OF MUSCLE FATİGUE İN SOCCER PLAYERS

Completed

Cardiac or pulmonary disease; Previous history of knee surgery or skeletal muscular dysfunctions in hip, knee or ankle joints; Athletic person (intensive anaerobic activity); None practiced of physical activity regularly; Medications usage

The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Contact the study team to confirm eligibility.

Primary Completion

December 2008

Actual (reported)

Study Completion

December 2008

Actual (reported)

Last Updated

March 16, 2011

Record last verified: 2011-03

Source record

Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.

Source: ClinicalTrials.gov.

JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.

Registry identifier: NCT00785811
Data provider: ClinicalTrials.gov
Source updated: 2011-03-16
Normalization version: ctgov-legacy-1

Open registry record

Source retrieved: 2026-10-25 22:25:34 UTC

Locations

BR(1)

Study Stopped

Effect of Chronic Supplementation of L-arginine in the Muscular Performance

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (2)

1

2

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (2)

1

2

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations