NCT00784641

Brief Summary

Evaluation of the clinical performance of a novel Bausch \& Lomb daily disposable contact lens when compared to the currently marketed Bausch \& Lomb SofLens® daily disposable contact lenses and the currently marketed Johnson and Johnson 1-Day Acuvue Moist contact lenses when worn by adapted soft contact lens wearers on a daily disposable basis.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
567

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Nov 2008

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 31, 2008

Completed
1 day until next milestone

Study Start

First participant enrolled

November 1, 2008

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 4, 2008

Completed
27 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2008

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2009

Completed
11.8 years until next milestone

Results Posted

Study results publicly available

October 6, 2020

Completed
Last Updated

October 6, 2020

Status Verified

September 1, 2020

Enrollment Period

1 month

First QC Date

October 31, 2008

Results QC Date

August 21, 2020

Last Update Submit

September 11, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Percentage of Participants With Favorable Responses for the Initial Lens Performance Survey

    The initial lens performance survey was administered at the Screening/Dispensing Visit. Scores were captured on a scale from 0 to 100, with 100 being the most favorable score. Favorable responses were defined as scores of 80 or greater.

    At dispensing

Study Arms (3)

Novel Bausch & Lomb Contact Lens

EXPERIMENTAL

Novel Bausch \& Lomb daily disposable contact lenses

Device: Novel Bausch & Lomb daily disposable contact lenses

SofLens

ACTIVE COMPARATOR

Bausch \& Lomb SofLens daily disposable contact lenses

Device: Bausch & Lomb SofLens daily disposable contact lenses.

Acuvue

ACTIVE COMPARATOR

Johnson and Johnson 1-Day Acuvue Moist contact lenses

Device: Johnson and Johnson 1-Day Acuvue Moist contact lenses

Interventions

Lenses to be worn and replaced daily for 2 weeks.

Novel Bausch & Lomb Contact Lens

Lenses to be worn and replaced daily for 2 weeks.

SofLens

Lenses to be worn and replaced daily for 2 weeks.

Acuvue

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subjects with VA correctable to 0.3 logMAR (driving vision) or better in each eye.
  • Subjects must have clear central corneas and be free of any anterior segment disorders.
  • Subjects must be myopic and require lens correction in both eyes.

You may not qualify if:

  • Subjects with any systemic disease affecting ocular health.
  • Subjects using any systemic or topical medications that will, in the Investigator's opinion, affect ocular physiology or lens performance.
  • Subjects wearing monovision, multifocal or toric contact lenses.
  • Subjects with grade 2 or greater slit lamp findings.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dr. James Ferrari

Rochester, New York, 14609, United States

Location

MeSH Terms

Conditions

Myopia

Condition Hierarchy (Ancestors)

Refractive ErrorsEye Diseases

Results Point of Contact

Title
Study Director
Organization
Bausch Health

Study Officials

  • Bev Barna

    Bausch & Lomb Incorporated

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 31, 2008

First Posted

November 4, 2008

Study Start

November 1, 2008

Primary Completion

December 1, 2008

Study Completion

January 1, 2009

Last Updated

October 6, 2020

Results First Posted

October 6, 2020

Record last verified: 2020-09

Locations